Search
Skip to Search Results- 11Medicine and Dentistry, Faculty of
- 10Medicine and Dentistry, Faculty of/Alberta Research Centre for Health Evidence (ARCHE)
- 4University of Alberta Library
- 4University of Alberta Library/Libraries Staff Publications
- 1Nursing, Faculty of
- 1Nursing, Faculty of/Health Systems
-
A descriptive analysis of a representative sample of pediatric randomized controlled trials published in 2007
Download2013-02-04
Hamm, Michele, Vandermeer, Ben, Thomson, Denise, Milne, Andrea, Tjosvold, Lisa, Klassen, Terry P., Curtis, Sarah, Hartling, Lisa
BACKGROUND: Randomized controlled trials (RCTs) are the gold standard for trials assessing the effects of therapeutic interventions; therefore it is important to understand how they are conducted. Our objectives were to provide an overview of a representative sample of pediatric RCTs published in...
-
A descriptive analysis of child-relevant systematic reviews in the Cochrane Database of Systematic Reviews
Download2013-02-04
Hartling, Lisa, Chisholm, Annabritt, Moher, David, Bow, Simon, Klassen, Terry P., Thomson, Denise, Tjosvold, Lisa, Klassen, Jeffrey
Background: Systematic reviews (SRs) are considered an important tool for decision-making. There has been no recent comprehensive identification or description of child-relevant SRs. A description of existing child-relevant SRs would help to identify the extent of available child-relevant...
-
2005
Swingler, G., Williams, K., Hartling, L., Moyer, V., Cramer, K., Klassen, T. P., Wiebe, N.
Background The delivery of optimal medical care to children is dependent on the availability of child relevant research. Our objectives were to: i) systematically review and describe how children are handled in reviews of drug interventions published in the Cochrane Database of Systematic Reviews...
-
Diagnosing Clinically Significant Dehydration in Children with Acute Gastroenteritis Using Noninvasive Methods: A Meta-Analysis
Download2015
Milne, Andrea, Hartling, Lisa, Vandermeer, Ben, Freedman, Stephen B.
OBJECTIVE: To determine the most accurate, noninvasive method of assessing dehydration. STUDY DESIGN: The following data sources were searched: electronic databases, gray literature, scientific meetings, reference lists, and authors of unpublished studies. Eligible studies were comparative...
-
Do health care institutions value research? A mixed methods study of barriers and facilitators to methodological rigor in pediatric randomized trials.
Download2012
Scott, S. D., Hamm, M. P., Hartling, L., Klassen, T. P., Moher, D.
Background Pediatric randomized controlled trials (RCTs) are susceptible to a high risk of bias. We examined the barriers and facilitators that pediatric trialists face in the design and conduct of unbiased trials. Methods We used a mixed methods design, with semi-structured interviews building...
-
Efficacy and safety of exogenous melatonin for secondary sleep disorders and sleep disorders accompanying sleep restriction: meta-analysis.
Download2006
Vandermeer, B., Hartling, L., Buscemi, N.., Baker, G., Klassen, T. P., Vohra, S., Pandya, R., Tjosvold, L., Hooton, N.
Objective To conduct a systematic review of the efficacy and safety of exogenous melatonin in managing secondary sleep disorders and sleep disorders accompanying sleep restriction, such as jet lag and shiftwork disorder. Data sources 13 electronic databases and reference lists of relevant...
-
2013-02-15
Klassen, Terry P., Plint, Amy C., Vandermeer, Ben, Tjosvold, Lisa, Hartling, Lisa, Fernandes, Ricardo M., Patel, Hema, Bialy, Liza M., Johnson, David W.
Background: Bronchodilators are commonly used for acute bronchiolitis, despite uncertain effectiveness. Objectives: To examine the efficacy and safety of epinephrine in children less than two with acute viral bronchiolitis. Search methods: We searched CENTRAL (2010, Issue 3) which contains the...
-
2015/18/12
Introduction: Non-invasive ventilation (NIV) in children has become an increasingly common modality of breathing support where pressure support is delivered through a mask interface or less commonly through other non-invasive interfaces. At this time, NIV is considered a first-line option for...
-
2013-02-15
Joffe, Ari, Vandermeer, Ben, Hartling, Lisa, Lequier, Laurance, Larsen, Bodil, Anton, Natalie, Tjosvold, Lisa
Background: Nutritional support in the critically ill child has not been well investigated and is a controversial topic within paediatric intensive care. There are no clear guidelines as to the best form or timing of nutrition in critically ill infants and children. Objectives: To assess the...
-
2009-01-01
Joffe, Ari R., Schulz, Christina, Rosychuk, Ronda J., Dyck, John, Rebeyka, Ivan M., Ross, David B., Cheung, Po-Yin, Schulz, Richard
During cardiopulmonary-bypass matrix-metalloproteinases released may contribute to ventricular dysfunction. This study was to determine plasma matrix-metalloproteinases in neonates after cardiopulmonary-bypass and their relation to post-operative course. A prospective observational study included...