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Fall 2017
Advancements in data acquisition technologies and the desire for rich data has led to an increase in the size of data collected from modern analytical instruments. With the aid of chemometric techniques, researchers are still able to glean more useful information from these kinds of data than...
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Spring 2016
The analysis of thousands of metabolites and lipids for discovery of metabolite biomarkers for disease monitoring and diagnosis requires the highest sensitivity and robust methods. Metabolomics is the study of metabolites found in the body, which can be used to discover biomarkers of disease or...
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Discovery and Targeted Approaches for Comparative Label-Free Proteomic Quantification via Mass Spectrometry
DownloadSpring 2023
Over the last few decades, the field of proteomics has developed rapidly owing to advancements in genomic and transcriptomic technologies contributing to the compilation of vast quantities of protein sequence libraries. Proteomics, the study of global protein composition in a biological system,...
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Quantitative Label-Free Comparative Proteomic Analyses of Eukaryotic Tissues via Mass Spectrometry
DownloadFall 2018
In recent years, rapid advances in genomic and transcriptomic sequencing technologies have enabled the compilation of vast libraries of protein sequences and thus an explosion in bioinformatics-based fields of research. Among these is proteomics – the study of global protein abundance within a...
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Theoretical understanding and method development for high performance liquid chromatography-mass spectrometry for environmental analysis
DownloadFall 2021
Method development is a fundamental key step for effective and efficient analytical separations and analyses. Of particular importance is method development for high performance liquid chromatography-mass spectrometry (HPLC-MS). Specifically, environmental analysis applications require dedicated...