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Skip to Search Results- 1Bajwa, Barinder
- 1Guo, Xinyang
- 1Hooton, Kevin M
- 1Li, Yunong
- 1Sousa Monteiro, Fernanda
- 1Tran, Tran TN
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Advancing Lipidomics through Method Development, Data Processing, and its Applications in Cancer Research
DownloadFall 2024
Lipidomics, a subfield of metabolomics, offers comprehensive insights into the lipid composition of biological systems. Lipids, comprising a broad class of biological molecules, are essential to several biological functions. They play critical roles in cell membrane formation, serving as...
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Chemical Characterization of Indoor Air Pollutants: Implications to Consumer and Occupational Health
DownloadFall 2024
Humans living in the contemporary societies find the majority of their time spent indoors, promoting awareness regarding indoor air quality over the past decades. The indoor environment has gained significant complicity due to an increasing variety of inhalable products consumed in our daily...
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Spring 2015
The objective of this work was to employ differential 13C/12C dansyl chloride (DnsCl) derivatization strategies for qualitative and quantitative profiling of amine- and phenol-containing metabolites by liquid chromatography electrospray ionization Fourier Transform ion cyclotron resonance mass...
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Development and Applications of Chemical Isotope Labeling Methods for Metabolome Sample Normalization and Liquid Chromatography-Mass Spectrometry-Based Metabolomics
DownloadFall 2015
Metabolomics refers to the global study of the metabolome of a biological system where comprehensive and systematic profiling of all metabolites in a given biological sample (i.e., the metabolome) is performed. As the end product of biological processes, the status of metabolites could reflect...
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Development of Chemical Isotope Labeling Liquid Chromatography Mass Spectrometry on Quadrupole-Orbitrap Mass Spectrometers for Metabolome Analysis
DownloadFall 2023
Chemical isotope labeling liquid chromatography-mass spectrometry (CIL LC-MS) is a powerful technique in metabolomics, offering extensive coverage of the metabolome. This method involves dividing metabolites into sub-groups based on their functional groups and subjecting them to specific labeling...
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Development of Data Processing Methods in Chemical Isotope Labeling Liquid Chromatography-Mass Spectrometry-Based Metabolomics
DownloadSpring 2019
Metabolomics is an active research field on the methods development for the analysis of small metabolites in biological systems. It provides powerful approaches that allow us to examine the variations in the metabolic profiles and is capable of detecting complex biological changes using...
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Fall 2017
The most often used biofluids in metabolomics and disease biomarker discovery studies in the literature include urine, processed blood (serum or plasma), and cerebral spinal fluid. While investigations using these biofluids have led to numerous innovations in the field of metabolomics, little...
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Spring 2021
Lipidomics aims to research lipid metabolism inside various samples or biological organisms. Through the research of lipidomics, information regarding the diversity, abundance, and function of lipids can determined. Although lipids can be categorized into 8 lipid classes, the variability between...