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- 2Kibukawa, Miho
- 2Klassen, John S.
- 2Macauley, Matthew S.
- 2Passey, Douglas A.
- 2Rankin, Robert
- 13Graduate and Postdoctoral Studies (GPS), Faculty of
- 13Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 7Biological Sciences, Department of
- 6Biological Sciences, Department of/Journal Articles (Biological Sciences)
- 4Chemistry, Department of
- 4Chemistry, Department of/Journal Articles (Chemistry)
- 2Department of Biological Sciences
- 2Department of Chemical and Materials Engineering
- 2Department of Chemistry
- 1Department of Agricultural, Food and Nutritional Science
- 1Department of Agricultural, Food, and Nutritional Science
- 1Department of Civil and Environmental Engineering
- 2Mahal, Lara (Chemistry)
- 1Betti, Mirko (Department of Agricultural, Food and Nutritional Science)
- 1Chan, Dave (Civil and Environmental Engineering)/Zhang, Guodong (Civil and Architecture)
- 1Feldman, Mario (Biological Sciences)
- 1Kurata, Harley (Pharmacology)
- 1Mario Feldman (Biological Sciences)
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Different scales of spatial segregation of two species of feather mites on the wings of a passerine bird
Download2011
Mestre, A., Mesquita-Joanes, F., Proctor, H., Monros, J. S.
The \"condition-specific competition hypothesis\" proposes that coexistence of 2 species is possible when spatial or temporal variations in environmental conditions exist and each species responds differently to those conditions. The distribution of different species of feather mites on their...
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Elevation of global O-GlcNAc levels in 3T3-L1 adipocytes by selective inhibition of O-GlcNAcase does not induce insulin resistance
Download2008
Bubb, Abigail K., Macauley, Matthew S., Davies, Gideon J., Vocadlo, David J. , Martinez-Fleites, Carlos
The O-GlcNAc post-translational modification is considered to act as a sensor of nutrient flux through the hexosamine biosynthetic pathway. A cornerstone of this hypothesis is that global elevation of protein O-GlcNAc levels, typically induced with the non-selective O-GlcNAcase inhibitor PUGNAc...
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2013
This essay analyzes and develops recent views about explanation in biology. Philosophers of biology have parted with the received deductive-nomological model of scientific explanation primarily by attempting to capture actual biological theorizing and practice. This includes an endorsement of...
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Exploiting bacterial glycosylation machineries for the synthesis of a Lewis antigen-containing glycoprotein
Download2011
Hug, Isabelle, Reiz, Bela, Fentabil, Messele A., Klassen, John S., Whittal, Randy M., Zheng, Blake, Feldman, Mario F.
Glycoproteins constitute a class of compounds of increasing importance for pharmaceutical applications. The manipulation of bacterial protein glycosylation systems from Gram-negative bacteria for the synthesis of recombinant glycoproteins is a promising alternative to the current production...
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Exploiting novel Acinetobacter Oligosaccharyltransferases for the development of glycoconjugate vaccines against the Pneumococcus
DownloadSpring 2016
Vaccines bring many diseases under control, an example of which is the Streptococcus pneumoniae, or the Pneumococcus. Pneumococcus is one of the leading causes of meningitis in children under 5 years, and is responsible for almost a million child deaths annually, with more than 90 serotypes...
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Spring 2015
Acinetobacter baumannii remains a poorly understood, but very dangerous opportunistic pathogen. Though it lacks clear virulence traits expected of pathogens, it none the less poses a massive threat to the hospital system due to its inherent and acquired resistance to antibiotics, survival on...
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Fall 2015
Bacterial resistance to chemical and physical methods in food processing, and the consumers’ demand for food free of chemical additives challenge the food industry to identify new approaches for food preservation. Affordable and novel antimicrobial compounds from food derived sources are an...
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Identification of atomistic mechanisms for grain boundary migration in [001] twist boundaries: molecular dynamics simulations
DownloadFall 2009
In this thesis, molecular dynamics simulations were performed to characterize the atomic motions governing grain boundary migration in a series of [001] twist boundaries. Particularly, migrations of a θ=36.87° Σ5, a θ=22.63° Σ13 and a θ=40.23° general high angle [001] twist boundaries driven by...
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2015
Klassen, John S., Yao, Yuyu, Serpe, Michael J., Xu, Wenwen
Anisotropic particles have generated an enormous amount of research interest due to their applications for drug delivery, electronic displays and as micromotors. However, up till now, there is no single protocol capable of generating particles of “patchy” composition with a variety of...