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- 12Macrophages
- 4Immunoregulatory receptors
- 3Comparative immunology
- 3Phagocytosis
- 2Broiler
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Identification and Molecular Characterization of Zebrafish (Danio rerio) Leukocyte Immune-Type Receptors (DrLITRs)
DownloadSpring 2020
In response to foreign invaders, innate immune cells use cell surface-expressed receptors to trigger intracellular signalling cascades that control various effector responses designed to destroy microbes. These specialized receptors are known as immunoregulatory receptors and structurally they...
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Improving chemotherapeutic regimens by mitigating hearing loss as a limiting side-effect and examining transition metal ions as a ligand for zebrafish Tlr4
DownloadFall 2023
Cancer is often a debilitating disease associated with the uncontrolled growth of cells within an organism. We have made significant strides over the past few decades in treating many cancers, unfortunately, many of these treatments have unfavourable side effects. Cisplatin is a revolutionary...
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Inhalable nanoparticles in lung cancer treatment; efficacy, safety, distribution and nanoparticle-macrophage interactions
DownloadFall 2012
In 2002, lung cancer was responsible for 17.6% of the total worldwide deaths from cancer. Beyond the three traditional forms of cancer treatment, surgery, radiation therapy, and chemotherapy, targeted drug delivery therapy has shown to be a potential treatment option. The design of a successful...
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Fall 2017
The two types of rejection identified in the Banff histopathologic diagnosis are T cell-mediated rejection (TCMR) and antibody-mediated rejection (ABMR). TCMR is most common early post-transplant while ABMR is the main cause of late graft loss. Kidney transplant TCMR is diagnosed histologically...
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Investigating Mechanisms Responsible for the Pro-Regenerative Effects of Conditioning Electrical Stimulation
DownloadFall 2022
Though capable of regeneration, repair surgeries following peripheral nerve injury are often incomplete or entirely unsuccessful. The slow rate of regeneration (1-3mm/day) of a proximal injury requires up to two years to reach the distal target, whereas significant muscle atrophy occurs after...
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Magazine Images Depicting the Ideal Fit Male Body: An Outlet for Influencing Body Perceptions and Exercise Related Cognitions
DownloadFall 2012
This study examined the effects of viewing health/fitness and sports magazine images on body perceptions and exercise related cognitions in males. The moderating effects of age were also examined. A series of 3 (image-only, magazine cover, control) by 3 (youngest, middle, oldest) ANOVA analyses...
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Monitoring Macrophage Immune Gene Expression Profiles as an Early Indicator System for Examining the Bioactivity of Oil Sands Process Affected Waters
DownloadFall 2021
Oil sands process-affected waters (OSPW) are by-products of bitumen (i.e. oil) extraction from the oil sands located in northern Alberta. These large volumes of water are held in tailings ponds and cannot be released due to their potential toxic effects. Overall, tailings ponds and mining...
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Fall 2013
Nutritional strategies to mitigate the loss of broiler performance due to the elimination of prophylactic antibiotics were investigated, consisting of two nutrient density starter diets (HIGH: 3,025 kcal/kg and 23.9% CP; LOW: 2,858 kcal/kg and 22.3% CP), 25-OH-D3 (0 or 69 µg/kg), and bacitracin...