Nutritional mitigation strategies for antibiotic free broiler production

• Author / Creator

  Ton, Kim Ph

• Nutritional strategies to mitigate the loss of broiler performance due to the elimination of prophylactic antibiotics were investigated, consisting of two nutrient density starter diets (HIGH: 3,025 kcal/kg and 23.9% CP; LOW: 2,858 kcal/kg and 22.3% CP), 25-OH-D3 (0 or 69 µg/kg), and bacitracin methylene disalicylate (BMD®110; 0.5g/kg). All groups received the same basal diet for grower (3,150 kcal/kg, 21.7% CP) and finisher phases (3,200 kcal/kg, 20.0% CP). On d 14, subsets of broilers (n=128) were randomly selected, and either injected with Salmonella typhimurium lipopolysaccharide, or remained non-injected (n=64). The LOW diet decreased breast yield, body weight, and feed efficiency. BMD reduced mortality and interleukin-1β mRNA expression. 25-OH-D3 increased expression of LPS-induced tumor necrosis factor alpha and inducible nitric oxide synthase mRNA in the non-LPS group. A necrotic enteritis outbreak could have increased inflammatory response in the 25-OH-D3 birds, and may have led to decrease breast yield in this group.

• Subjects / Keywords

  • Ileal morphology
  • Innate immunity
  • 25 hydroxy vitamin D3
  • Pro-inflammatory cytokine genes
  • Broiler

• Graduation date

  Fall 2013

• Type of Item

  Thesis

• Degree

  Master of Science

• DOI

  https://doi.org/10.7939/R3K97W

• License

  This thesis is made available by the University of Alberta Libraries with permission of the copyright owner solely for non-commercial purposes. This thesis, or any portion thereof, may not otherwise be copied or reproduced without the written consent of the copyright owner, except to the extent permitted by Canadian copyright law.