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Fall 2009
One important goal in microarray data analysis is to learn a predictor using a patient’s microarray data to predict some important characteristics of that patient. The high dimensionality of data makes learning such classifiers very challenging. We tried to use prior biological knowledge to...
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1987
Owttrim, George W., Coleman, John R.
A recA-like gene isolated from the cyanobacterium Anabaena variabilis was cloned and partially characterized. When introduced into Escherichia coli recA mutants, the 7.5-kilobase-pair plasmid-borne DNA insert restored resistance to methyl methanesulfonate and UV irradiation, as well as...
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2005-09-01
Samudrala, Ram , Zheng, Hongkun , Li, Jun, Yang, Shuang , Zhang, Jianguo , Yu, Haijing , McDermott, Jason , Wang, Wen , Yang, Huanming , Jiang, Huifeng , Yang, Lei , Wang, Jian , Wong, Gane K., Kristiansen, Karsten , Su, Jianning , Yu, Jun
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2014-12-09
CIHR Institute of Nutrition, Metabolism, and Diabetes
The CIHR Institute of Nutrition, Metabolism, and Diabetes recently hosted an information webinar describing the program, what funds are available, the four funding pools, collaborators and partners, deadlines and evaluation criteria. The webinar slides can now be downloaded.
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ReAS: Recovery of Ancestral Sequences for Transposable Elements from the Unassembled Reads of a Whole Genome Shotgun
Download2005
Ye, C., Wang, J., Li, S., Li, R., Wong, G.K.S., Ye, J., Yang, H., Han, Y., Yu, J.
We describe an algorithm, ReAS, to recover ancestral sequences for transposable elements (TEs) from the unassembled reads of a whole genome shotgun. The main assumptions are that these TEs must exist at high copy numbers across the genome and must not be so old that they are no longer...
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1989
Coleman, John R. , Owttrim, George W.
The expression of the cyanobacterial recA gene, isolated from Anabaena variabilis, has been examined at the levels of transcript and protein abundance. Exposure of the cyanobacterium to a variety of DNA-damaging agents, including mitomycin C, methyl methanesulfonate, and UV irradiation, results...
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2000
This paper points to some problems for the position that D.M. Walsh calls \"alternative individualism,\" and argues that in defending this view Walsh has omitted an important part of what separates individualists and externalists in psychology. Walsh's example of Hox gene complexes is discussed...
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The mitochondrial genome of the hexactinellid sponge Aphrocallistes vastus: Evidence for programmed translational frameshifting
Download2008
Rosengarten, R.D., Sperling, E.A., Leys, S.P., Dellaporta, S.L., Moreno, M.A.
Background: Mitochondrial genomes (mtDNA) of numerous sponges have been sequenced as part of an ongoing effort to resolve the class-level phylogeny of the Porifera, as well as to place the various lower metazoan groups on the animal-kingdom tree. Most recently, the partial mtDNA of two glass...