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Alternative Requirements for Vestigial, Scalloped, and Dmef2 during Muscle Differentiation in Drosophila melanogaster
Download2009
Bell, J. B., Deng, H., Simmonds, A. J., Hughes, S. C.
Abstract: Vertebrate development requires the activity of the myocyte enhancer factor 2 (mef2) gene family for muscle cell specification and subsequent differentiation. Additionally, several muscle-specific functions of MEF2 family proteins require binding additional cofactors including members...
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BGI-RIS: An integrated information resource and comparative analysis workbench for rice genomics
Download2004
Wang, J., Chen, Y., Zhao, H., Dai, M., Zhao, W., Huang, X., Zhang, Y., Ren. X., Jiao, Y., Wong, G., Wei, S., Ni, P., Yu, J., Zhang, J., Li, S., Yang, H., Fu, J., He, X.
Rice is a major food staple for the world's population and serves as a model species in cereal genome research. The Beijing Genomics Institute (BGI) has long been devoting itself to sequencing, information analysis and biological research of the rice and other crop genomes. In order to facilitate...
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The construction and use of bacterial DNA microarrays based on an optimized two-stage PCR strategy
Download2003
Li, H., Klahn, J., Galbraith, D.W., Deyholos, M., Sherman, L.A., Impson, L., Postier, B.L., Risinger, G., Andrews, H.L., Burnap, R.L., Pesta, D., Wang, H.L., Singh, A.
Background: DNA microarrays are a powerful tool with important applications such as global gene expression profiling. Construction of bacterial DNA microarrays from genomic sequence data using a two-stage PCR amplification approach for the production of arrayed DNA is attractive because it...
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ReAS: Recovery of Ancestral Sequences for Transposable Elements from the Unassembled Reads of a Whole Genome Shotgun
Download2005
Ye, C., Wang, J., Li, S., Li, R., Wong, G.K.S., Ye, J., Yang, H., Han, Y., Yu, J.
We describe an algorithm, ReAS, to recover ancestral sequences for transposable elements (TEs) from the unassembled reads of a whole genome shotgun. The main assumptions are that these TEs must exist at high copy numbers across the genome and must not be so old that they are no longer...
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Functional genomics of mountain pine beetle (Dendroctonus ponderosae) midguts and fat bodies
Download2010-01-01
Keeling, Christopher I., Bearfield, Jeremy C., Blomquist, Gary J., Schlauch, Karen, Tittiger, Claus, Young, Sharon, Aw, Tidiane
Background The mountain pine beetle (Dendroctonus ponderosae) is a significant coniferous forest pest in western North America. It relies on aggregation pheromones to colonize hosts. Its three major pheromone components, trans-verbenol, exo-brevicomin, and frontalin, are thought to arise via...
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Generation, annotation, analysis and database integration of 16,500 white spruce EST clusters
Download2005
Johnson, J.E., Pavy, N., Cooke, J., Parsons, L., Paule, C., Morency, M.J., Crow, J.A.
Background: The sequencing and analysis of ESTs is for now the only practical approach for largescale gene discovery and annotation in conifers because their very large genomes are unlikely to be sequenced in the near future. Our objective was to produce extensive collections of ESTs and cDNA...
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Molecular cloning, pharmacological characterization and brain mapping of the melanocortin 4 receptor in the goldfish: Involvement in the control of food intake
Download2003
Schioth, H.B., Cerdá-Reverter, J.M., Peter, R.E., Ringholm, A.
We report cloning, pharmacological characterization, tissue distribution, detailed brain mapping, and role in control of food intake of melanocortin 4 receptor in goldfish (gMC4R). The gMC4R protein has 68% identity with the human ortholog and is conserved in important functional domains....
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Acid-base properties of cyanobacterial surfaces II: Silica as a chemical stressor influencing cell surface reactivity
Download2008
Owttrim, G.W., Lalonde, S.V., Smith, D.S., Konhauser, K.O.
Bacteria grow in complex solutions where the adsorption of aqueous species and nucleation of mineral phases on the cell surface may interfere with membrane-dependent homeostatic functions. While previous investigations have provided evidence that bacteria may alter their surface chemical...
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Gawky Is a Component of Cytoplasmic mRNA Processing Bodies Required for Early Drosophila Development
Download2006
Hobman, T. C., Locker, J., Schneider, M. D., Pare, J. M., Haskins, J., Simmonds, A. J., Chaker, S., Najand, N
In mammalian cells, the GW182 protein localizes to cytoplasmic bodies implicated in the regulation of messenger RNA ( mRNA) stability, translation, and the RNA interference pathway. Many of these functions have also been assigned to analogous yeast cytoplasmic mRNA processing bodies. We have...