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Skip to Search Results- 2Elamy, Abdel-Halim H
- 1Achtymichuk, Karly A
- 1Adams, Scott C
- 1Akinwumi, Segun M
- 1Alabi, Adekunle
- 1Aldana Hernandez, Paulina
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Fall 2012
Cholera remains epidemic and endemic in the world, causing thousands of deaths annually in locations lacking adequate sanitation and water infrastructure. Yet its dynamics are still not fully understood. An indirectly transmitted infectious disease model, called an iSIR model, was recently...
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Spring 2023
Atherosclerosis and aortic aneurysms are two major vascular diseases, and extracellular matrix (ECM) plays an important role in both as a non-cellular component of the aortic wall that also regulates vascular cell behavior and function. Atherosclerosis is a major contributor to cardiovascular...
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Fall 2017
Phosphatidylethanolamine N-methyltransferase (PEMT) is a hepatic enzyme that converts phosphatidylethanolamine to phosphatidylcholine. Pemt-/- mice are protected from obesity and insulin resistance, a phenotype that is reversed with dietary choline supplementation. Additionally, PEMT deficiency...
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The Role of Intestinal Derived Remnant Lipoproteins in the Progression of Atherosclerosis in Animal Models of Type 1 and Type 2 Diabetes.
DownloadFall 2011
Introduction: Subjects with insulin resistance (IR) and diabetes are at increased risk of cardiovascular disease (CVD) than those without diabetes, however the mechanistic basis remains elusive. Despite LDL-cholesterol lowering by statin therapy, two-thirds of all CVD events remain, constituting...
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Epidemiology and Use of Health Services for Chronic Obstructive Pulmonary Disease among Aboriginal Peoples in Alberta: Insights into Aboriginal Peoples’ Respiratory Health
DownloadFall 2013
Background: Chronic obstructive pulmonary disease (COPD) is a major respiratory disorder and a leading cause of morbidity and mortality. There is limited information about the burden of disease for COPD among Aboriginal peoples in Canada. Objectives: To compare the epidemiology and patterns of...
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Investigating the role of coiled-coil domain containing protein 3 (CCDC3), a novel secreted protein, in endothelial inflammation
DownloadFall 2015
Endothelial inflammation is critical in the initiation and progression of atherosclerosis and other cardiovascular diseases (CVDs). Tumor necrosis factor-α (TNF-α) is a pro-inflammatory cytokine that induces endothelial inflammation via activation of nuclear factor κB (NF-κB) signaling....
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Examining Associations of Community Food Environments with Individual Diet Quality and Body Weight Status of Canadian Children
DownloadFall 2019
Reducing the prevalence of unhealthy eating is an important challenge to address in order to reduce the burden of obesity and chronic disease. Approximately 1.6 million or one-third of Canadian children and youth are overweight or obese, and about 70% of children and youth consume less than five...
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Antimicrobial Resistant Campylobacter species in the Food Chain: Understanding the Human Risk of Infection
DownloadFall 2022
Background: Campylobacter spp., commonly detected in poultry, are the third most common cause of foodborne illness in Canada. Campylobacter while self-limiting and typically only requiring supportive care treatment, can be resistant to antimicrobials important to human health. To better...
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Spring 2022
Carotid atherosclerosis is responsible for 15-25% of the nearly 8 million first-ever ischemic strokes that occur each year worldwide. This proportion has remained constant over the past three decades, thus suggesting that some patients with carotid atherosclerosis currently receive suboptimal...
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Effects of High-Intensity Aerobic Interval Training on Cardiovascular Disease Risk and Health-related Quality of Life in Testicular Cancer Survivors: The HIITTS Trial
DownloadFall 2017
Background: Testicular cancer (TC) survivors (TCS) are an understudied, high-risk group susceptible to late-onset treatment-related cardiovascular disease (CVD), psychosocial, and health-related quality of life (HRQoL) deficits in the years following treatment. Importantly, despite having the...