Search
Skip to Search Results- 12Klassen, John S.
- 8Kitova, Elena N.
- 4Richards, Michele R.
- 3Han, Ling
- 3Yao, Yuyu
- 2Armstrong, Glen D.
- 70Graduate and Postdoctoral Studies (GPS), Faculty of
- 70Graduate and Postdoctoral Studies (GPS), Faculty of /Theses and Dissertations
- 15Biological Sciences, Department of
- 15Biological Sciences, Department of/Journal Articles (Biological Sciences)
- 14Chemistry, Department of
- 14Chemistry, Department of/Journal Articles (Chemistry)
-
2016
Richards, Michele R., Campuzano, Iain D. G., Kitova, Elena N., Klassen, John S., Li, Jun, Privé, Gilbert G., Xiong, Zi Jian, Bagal, Dhanashri
Saposin A (SapA) lipoprotein discs, also known as picodiscs (PDs), represent an attractive method to solubilize glycolipids for protein interaction studies in aqueous solution. Recent electrospray ionization mass spectrometry (ESI-MS) data suggest that the size and composition of...
-
Spring 2015
The objective of this work was to employ differential 13C/12C dansyl chloride (DnsCl) derivatization strategies for qualitative and quantitative profiling of amine- and phenol-containing metabolites by liquid chromatography electrospray ionization Fourier Transform ion cyclotron resonance mass...
-
Comparative analysis of two phenotypically-similar but genomically-distinct Burkholderia cenocepacia-specific bacteriophages
Download2012
Stothard, Paul, Dennis, Jonathan J., Lynch, Karlene H.
Background Genomic analysis of bacteriophages infecting the Burkholderia cepacia complex (BCC) is an important preliminary step in the development of a phage therapy protocol for these opportunistic pathogens. The objective of this study was to characterize KL1 (vBBceSKL1) and AH2 (vBBceSAH2),...
-
Spring 2016
One of the key obstacles to the effective use of mass spectrometry (MS) in high throughput metabolomics is the difficulty in interpreting measured spectra to accurately and efficiently identify metabolites. Traditional methods for automated metabolite identification compare the target MS spectrum...
-
Fall 2016
α-Synuclein has been implicated in the progression of Parkinson’s disease, a neurodegenerative disorder that affects millions of people worldwide. This work reports on the structural propensity and druggability of this protein using a combination of Monte Carlo, Molecular Dynamics, and Virtual...
-
Computational support systems for prediction and characterization of protein crystallization outcomes
DownloadFall 2013
Analysis of protein structures may reveal their function, regulation and interactions. Almost 90% of the known protein structures were solved using X-ray crystallography; however, many more structures remain unsolved. Protein Structure Initiative (PSI) project was created to speed up structure...
-
2012
Law, G. K., Forbes, J. F., Elliott, J. A., McGann, L. E., Jomha, N. M., Prasad, V., Almansoori, K. A.
Background Vitrification is a method of cryopreservation by which cells and tissues can be preserved at low temperatures using cryoprotective agents (CPAs) at high concentrations (typically ⩾6.0 M) to limit the harmful effects of ice crystals that can form during cooling processes. However, at...
-
Crystallization and preliminary diffraction studies of TraF, a component of the Escherichia coli type IV secretory system
Download2004
Manchak, J., Hayakawa, K., Audette, G.F., Holland, S.J., Frost, L.S., Hazes, B.
TraF, a component of the Escherichia coli type IV secretory system, has been crystallized and preliminary X-ray diffraction data have been collected. TraF is a 26 kDa protein encoded by the E. coli F plasmid and is required for conjugative plasmid transfer and the formation of sex pili. The...
-
2014-10-27
Wu, Xiaolei , Wafula, Eric , Yan, Zhixiang , Kutchan, Toni M. , Gitzendanner, Matthew A, Shaw, Jonathan A., Chen, Tao. , Wickett, Norman J., Nguyen, Nam , Burleigh, J Gordon , Miles, Nicholas W. , Soltis, Pamela S. , Melkonian, Michael , Deyholos, Michael K. , Matasci, Naim , DeGironimo, Lisa , Samudrala, Ram , Leebens-Mack, Jim , Mirarab, Siavash , Barker, Michael , Sun, Xiao , Soltis, Douglas E. , Rolf, Megan , Tian, Zhijian , Wong, Gane K, Rothfels, Carl , Pokorny, Lisa , Zhang, Yong , Ayyampalayam, Saravanaraj , Graham, Sean W. , Roure, Béatrice, Der, Joshua P., Wang, Jun , Mathews, Sarah , Surek, Barbara , Baucom, Regina S. , Ruhfel, Brad R. , Villarreal, Juan C., Stevenson, Dennis W. , Hung, Ling-Hong , Warnow, Tandy , Philippe, Hervé , Carpenter, Eric J.
The 1,000 plants (1KP) project is an international multi-disciplinary consortium that has generated transcriptome data from over 1,000 plant species, with exemplars for all of the major lineages across the Viridiplantae (green plants) clade. Here, we describe how to access the data used in a...