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Skip to Search Results- 1Azam Nikzad
- 1Baedke, Jessica
- 1Barazandeh, Marjan
- 1Barrett, Kimberley G
- 1Ciechanowska, Izabela L.
- 1Clark, Laura Ashley
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Fall 2010
Improving feed efficiency has become a top priority in beef cattle production because of the rapidly increasing cost of feed provision. However, because of the expense associated with collecting individual animal feed intake data, only a relatively small number of animals have been tested,...
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Assessing the Feasibility of Learning Biomedical Phenotype Patterns Using High-Throughput Omics Profiles
DownloadSpring 2014
A decade after the completion of the human genome project, the rapid advancement of the high-throughput measurement technologies has made omics (genomics, epigenomics, transcriptomics, metabolomics) profiling feasible. The availability of such omics profiles has raised the hope for the...
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Association analyses of SNPs in candidate genes with body fat deposition and carcass merit traits in beef cattle
DownloadFall 2009
A candidate gene approach was used to identify single nucleotide polymorphisms (SNPs) and their associations with body fat deposition and carcass merit traits in beef cattle. In total, 37 SNPs from 9 candidate genes have been genotyped on 463 hybrid, 206 Angus and 187 Charolais steers for...
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Chronic Fatigue Mechanisms in Autoimmune Diseases: Lessons from Primary Biliary Cholangitis and Systemic Sclerosis
DownloadFall 2023
Systemic sclerosis (SSc) is an autoimmune disease affecting the body's connective tissues, resulting in progressive fibrosis and vasculopathy. In some cases, individuals with SSc may also develop primary biliary cholangitis (PBC), another autoimmune disease characterized by damage to their...
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Fall 2014
An individual’s body weight is tightly regulated by balancing food intake with energy expenditure. This is accomplished in part by secretion of the hormone leptin by adipocytes, an excess of which signals to reduce appetite and increase activity through action in the hypothalamic region of the...
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Spring 2019
DNA-templated reactions have been utilized in many applications from the detection of a nucleic acid target to applications in nanotechnology. This thesis explores developing bioanalytical strategies based on DNA-templated ligation reactions for sensitive, rapid single nucleotide polymorphism...
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Genetic structure of a large recolonizing carnivore: the case of the northern cougars (Puma concolor)
DownloadFall 2023
Anthropogenic activities have pressured and altered landscapes resulting in extinctions and extirpations. However, increased conservation efforts and changing management strategies in some large carnivores have resulted in population and range expansion. Population growth and range expansion are...
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Fall 2019
The development of efficacious anticancer therapies has significantly improved the prognosis of childhood cancer patients at the price of predisposing survivors to extensive chronic health problems. Although not fatal, reducing treatment-related hearing loss (ototoxicity) among childhood cancer...
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Identification of Shared and Distinct Gene-disease Associations Among Multiple Related Diseases and Multiple Subtypes of a Disease
DownloadFall 2013
Genome-wide association study (GWAS) is an approach with high-throughput genotyping to uncover genetic susceptibilities of complex diseases. However, the genetic susceptibilities discovered usually carry very small risk increments. Additionally, the current approach to assess whether these...
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Mapping QTLs for different traits in conventional and organic management systems and evaluating the effects of Lr34/Yr18 and Lr37/Yr17 in a Canadian western hard spring wheat population
DownloadSpring 2019
Canadian western red spring wheat (CWRS) has been predominantly cultivated class in Western Canada, because of its premium quality attributes and excellent adaptability to the relatively short growing season. Early maturity, short plant stature, higher grain yield, protein content and dough...