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Skip to Search Results- 1Aghamohammadi Sereshki, Arash
- 1Bhardwaj, Paramjit P
- 1Fahreen, Rajani I.
- 1Ferdousi, Mehnaz I
- 1Fung, Terry L
- 1Guo, Huining
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Spring 2016
Depression is a common, recurrent and frequently chronic mental health disorder that has already become one of the leading health-care burdens. Despite the wide clinical application of antidepressants, a significant portion of patients does not benefit sufficiently from the standard medication...
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The Role of Vitamin D in Anti-Tumor Necrosis Factor-Alpha-Induced Response in Patients with Inflammatory Bowel Disease
DownloadFall 2014
Vitamin D is an important immunomodulator of the immune system and has been suggested to play a role in the pathogenesis of inflammatory bowel disease (IBD). Drugs targeting TNF-alpha are effective IBD therapies, and vitamin D has been demonstrated to suppress TNF-alpha as well as work...
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Links Between Depressive Symptoms, Sexual Communication, and Sexual Satisfaction Across Three Years
DownloadSpring 2021
Guided by a relational developmental systems perspective, stress generation hypothesis, and gender relations theory, this thesis examined two major research questions: (1) What are the longitudinal associations between self-reported depression symptoms, sexual communication, and sexual...
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Structural changes of the amygdala subnuclei and limbic white matter tracts in healthy aging and major depressive disorder
DownloadFall 2019
The world population is dramatically aging. Several factors affect brain in healthy aging. The apolipoprotein E (APOE), brain-derived neurotrophic factor (BDNF) and catechol-O-methyl transferase (COMT) might be involved in neurodegenerative diseases, depression and cognitive decline in healthy...
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Exploring the Relationship Between Depression and Adherence in Individuals with Type 2 Diabetes
DownloadFall 2020
Background: Depression is a well-known risk factor for poor medication adherence in individuals with diabetes; however, this association is based on cross-sectional and cohort studies measuring adherence after depression is diagnosed. Symptoms of depression often progress before medical...
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Depression of Lead-activated Sphalerite by Sodium Hydrogen Phosphate for Red Dog Mine Operation
DownloadSpring 2019
The inadvertent activation of sphalerite by lead ions have been noticed and studied for decades. In this study, flotation behavior of sphalerite upon lead activation was studied. Sodium hydrogen phosphate was applied as a main depressant to test its effect on improving Pb-Zn selectivity. Surface...
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Hippocampal neuroplasticity and neurogenesis in major depressive disorder: a high field MRI study
DownloadFall 2012
The hippocampus is a brain structure responsible for memory, learning, and the stress response; it is also used as a model for major depressive disorder (MDD) in preclinical studies. Preclinical models have shown that the hippocampal subfields are differentially affected by chronic stress....
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The Development, Feasibility, Acceptability, and Efficacy of a 12-Week Online Mind-Body Intervention for People with Primary Biliary Cholangitis
DownloadFall 2022
Introduction: Persons with primary biliary cholangitis (PBC) experience significantly higher rates of mental distress, impaired health related quality of life (HrQoL), and fatigue than the general population. While mind-body interventions have been shown to improve mental health and HrQoL, and...
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Spring 2022
Nowadays, with the rapid development of science and technology, human healthcare has become a hot topic and attracts more and more attention. A lot of researchers work on different technologies to contribute to our healthcare no matter disease diagnosis and prognosis or disease treatment. In this...
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Structure-Affinity Relationship Study of Novel Imidazoline Ligands at Imidazoline Binding Sites and α-Adrenoceptors
DownloadFall 2014
Many drugs containing an imidazoline moiety are thought to bind to both imidazoline binding sites (IBS) and α-adrenoceptors (α-AR) to mediate their therapeutic effects. To aid in better characterisation of these binding sites, the structure-affinity relationships of several new series of...