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Skip to Search Results- 52Mass-spectrometry
- 8Metabolomics
- 6Cytotoxicity
- 5Electrospray ionization
- 4Classification
- 4Proteomics
- 6Klassen, John S.
- 4Kitova, Elena N.
- 3Han, Ling
- 2Armstrong, Glen D.
- 2Dingle, Tanis C.
- 2El-Hawiet, Amr
- 44Graduate and Postdoctoral Studies (GPS), Faculty of
- 44Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 7Chemistry, Department of
- 7Chemistry, Department of/Journal Articles (Chemistry)
- 2Biological Sciences, Department of
- 2Biological Sciences, Department of/Journal Articles (Biological Sciences)
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2009
Wishart, D.S., Psychogios, N., Young, N., Xia, J.
Metabolomics is a newly emerging field of ‘omics’ research that is concerned with characterizing large numbers of metabolites using NMR, chromatography and mass spectrometry. It is frequently used in biomarker identification and the metabolic profiling of cells, tissues or organisms. The data...
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Modeling the Colchicum autumnale Tubulin and a Comparison of Its Interaction with Colchicine to Human Tubulin
Download2017-08-02
Ayoub, Ahmed T , Dumonte, Charles, Wong, Gane K-S, Preto, Jordane, Tuszynski, Jack A, Spasevska, Ivana, Winter, Philip
Tubulin is the target for many small-molecule natural compounds, which alter microtubules dynamics, and lead to cell cycle arrest and apoptosis. One of these compounds is colchicine, a plant alkaloid produced by Colchicum autumnale. While C. autumnale produces a potent cytotoxin, colchicine, and...
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2004
Technical report TR04-10. This report overviews the Mass Spectrometry Data Classification and Feature Extraction problem. After reviewing previous research new classification and feature extraction techniques are presented and empirically evaluated on three data sets. One of the key points made...
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Quantitative Characterization of Noncovalent Protein-Carbohydrate Interactions using Electrospray Ionization Mass Spectrometry
DownloadFall 2015
The interactions between water-soluble proteins and carbohydrates found on the surfaces of cells play important roles in many physiological and pathological cellular processes. Carbohydrates function as receptors for signaling, cellular recognition and adhesion, and pathogen infections. This...
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Fall 2009
Cytotoxic T lymphocytes (CTL) are differentiated CD8+ T cells that eliminate virally infected cells and tumor cells. CTL lyse target cells by at least two distinct mechanisms: degranulation of cytolytic molecules and cell surface expression of Fas ligand (FasL), which induces apoptosis of...
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Fall 2011
Liquid crystalline domains were observed in fractions of heavy petroleum. Through a combination of polarized light microscopy and Photoacoustic Infrared Spectroscopy, liquid crystals were shown to form on the exterior surface of their parent materials. Analysis of materials using Differential...
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Separation and characterization of polycyclic aromatic hydrocarbons and azaarenes using normal phase liquid chromatography and electrospray ionization mass spectrometry
DownloadFall 2016
Normal phase liquid chromatography (NPLC) is widely used for separating petroleum into compound classes, such as polycyclic aromatic hydrocarbons (PAHs) and polar nitrogen containing compounds. The charge-transfer and hypercrosslinked polystyrene NPLC phases provide unique selectivities for PAHs....
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Spring 2017
A phenylarsenical, 3-nitro-4-hydroxyphenylarsonic acid (Roxarsone®, Rox), has been used extensively as a poultry feed additive for over 60 years. However, little is known about the concentrations of different arsenic species present in chicken meat as a consequence of feeding Rox to chickens....