Search
Skip to Search Results- 12Colorectal cancer
- 2Body composition
- 2Disease distribution
- 2Liver metastases
- 2Muscle
- 2Resting energy expenditure
- 9Graduate and Postdoctoral Studies (GPS), Faculty of
- 9Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 3Surgery, Department of
- 3Surgery, Department of/General Surgery
- 1Agricultural, Food and Nutritional Science, Department of
- 1Agricultural, Food and Nutritional Science, Department of/Journal Articles (Agricultural, Food and Nutritional Science)
-
Fall 2011
This study determined how chemotherapy treatment for colorectal cancer alters hepatic fat metabolism. Livers were isolated from tumor-bearing animals after one and two cycles of chemotherapy consisting of irinotecan plus 5-fluorouracil. Fatty acid amounts and composition within triglycerides (TG)...
-
Fall 2012
Mechanisms underlying fat loss in cancer are not well understood. Knowing the types of fat being lost from adipose tissue may help define interventions to circumvent wasting. The aim of this study was to explore the differences in adipokines and fatty acid composition between visceral adipose...
-
An exploration into the relationship of body composition parameters and survival outcomes in patients with resectable colorectal cancer
DownloadFall 2018
Both tumor biology and host-specific factors play an important role in the prognosis of colorectal cancer. Body composition is an emerging patient-specific factor, which is currently being elucidated. Opportunistic analysis of pre-existing staging computed tomography scans can be used to quantify...
-
Fall 2010
The purpose of this work was to further understand nutritional status, especially body weight and composition, during colorectal cancer progression. Population-based studies of colorectal cancer patients were conducted using administrative health data (primary and co-morbid diseases,...
-
Spring 2013
Gestational weight gain (GWG) is associated with short-and long-term maternal and infant health outcomes. The purpose of this research was to describe longitudinal changes in weight and body composition during pregnancy and early postpartum according to pre-pregnancy body mass index (BMI)...
-
Muscle Abnormalities in Colorectal Cancer: Exploring the Associations of Muscle Abnormalities with Pre-existing Comorbidities, and Adverse Surgical Outcomes in Non-metastatic Colorectal Cancer Patients
DownloadSpring 2018
The aim of this project was to further understand the association of pre-existing comorbidities and adverse surgical outcomes with muscle abnormalities in patients with non-metastatic colorectal cancer (CRC). Computerized tomographpy (CT) imaging was used for body composition assessment, and...
-
Protein Recommendation to Increase Muscle (PRIMe): Study protocol for a randomized controlled pilot trial investigating the feasibility of a high protein diet to halt loss of muscle mass in patients with colorectal cancer
Download2021-02-01
Ford, Katherine L., Sawyer, Michael B., Trottier, Claire F., Ghosh, Sunita, Deutz, Nicolaas E. P., Siervo, Mario, Porter Starr, Kathryn N., Bales, Connie W., Disi, Ilana Roitman, Prado, Carla M.
Background Severe muscle mass (MM) loss is a defining feature of cancer observed across all types and stages of disease and is an independent predictor of poor clinical outcomes including higher incidences of chemotherapy toxicity and decreased survival. Protein is essential to build MM, yet the...
-
2012
Birch, Daniel W., Gill, Richdeep S., Karmali, Shahzeer, Whitlock, Kevin
Obesity has become a major issue for healthcare providers as its prevalence continues to increase throughout the world. The literature suggests that increased body mass index (BMI) is associated with the development of certain cancers such as colorectal cancer (CRC). Consequently, CRC surgeons...