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A descriptive analysis of a representative sample of pediatric randomized controlled trials published in 2007
Download2013-02-04
Hamm, Michele, Vandermeer, Ben, Thomson, Denise, Milne, Andrea, Tjosvold, Lisa, Klassen, Terry P., Curtis, Sarah, Hartling, Lisa
BACKGROUND: Randomized controlled trials (RCTs) are the gold standard for trials assessing the effects of therapeutic interventions; therefore it is important to understand how they are conducted. Our objectives were to provide an overview of a representative sample of pediatric RCTs published in...
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A descriptive analysis of child-relevant systematic reviews in the Cochrane Database of Systematic Reviews
Download2013-02-04
Hartling, Lisa, Chisholm, Annabritt, Moher, David, Bow, Simon, Klassen, Terry P., Thomson, Denise, Tjosvold, Lisa, Klassen, Jeffrey
Background: Systematic reviews (SRs) are considered an important tool for decision-making. There has been no recent comprehensive identification or description of child-relevant SRs. A description of existing child-relevant SRs would help to identify the extent of available child-relevant...
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2014
Hamm, M. P., Shulhan, J., Milne, A., Williams, G., Scott, S. D., Hartling, L.
Background: Social media use is highly prevalent among children, youth, and their caregivers, and its use in healthcare is being explored. The objective of this study was to conduct a systematic review to determine: 1) for what purposes social media is being used in child health and its...
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Do health care institutions value research? A mixed methods study of barriers and facilitators to methodological rigor in pediatric randomized trials.
Download2012
Scott, S. D., Hamm, M. P., Hartling, L., Klassen, T. P., Moher, D.
Background Pediatric randomized controlled trials (RCTs) are susceptible to a high risk of bias. We examined the barriers and facilitators that pediatric trialists face in the design and conduct of unbiased trials. Methods We used a mixed methods design, with semi-structured interviews building...
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2013-02-15
Klassen, Terry P., Plint, Amy C., Vandermeer, Ben, Tjosvold, Lisa, Hartling, Lisa, Fernandes, Ricardo M., Patel, Hema, Bialy, Liza M., Johnson, David W.
Background: Bronchodilators are commonly used for acute bronchiolitis, despite uncertain effectiveness. Objectives: To examine the efficacy and safety of epinephrine in children less than two with acute viral bronchiolitis. Search methods: We searched CENTRAL (2010, Issue 3) which contains the...
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2013-02-15
Joffe, Ari, Vandermeer, Ben, Hartling, Lisa, Lequier, Laurance, Larsen, Bodil, Anton, Natalie, Tjosvold, Lisa
Background: Nutritional support in the critically ill child has not been well investigated and is a controversial topic within paediatric intensive care. There are no clear guidelines as to the best form or timing of nutrition in critically ill infants and children. Objectives: To assess the...
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Systematic Review of Knowledge Translation Strategies to Promote Research Uptake in Child Health Settings
Download2016
Snelgrove-Clarke, Ema, Archibald, Mandy, Albrecht, Lauren, Scott, Shannon D.
Background: Strategies to assist evidence-based decision-making for healthcare professionals are crucial to ensure high quality patient care and outcomes. The goal of this systematic review was to identify and synthesize the evidence on knowledge translation interventions aimed at putting...