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Skip to Search Results- 1Abdul Rahman, Siti Aishah
- 1Alles, Sascha R
- 1Chen, Yishen
- 1Dimopoulos, Ioannis
- 1Ferreira Marques, Elisa
- 1Gawad Gad,Sandra Sabry
- 5Centre for Neuroscience
- 4Department of Agricultural, Food, and Nutritional Science
- 3Department of Agricultural, Food and Nutritional Science
- 3Department of Pharmacology
- 3Department of Physiology
- 3Neuroscience
- 2Tse, Amy (Centre for Neuroscience and Department of Pharmacology)
- 1Alexander, Trevor (AAFC)
- 1Ballanyi, Klaus (Physiology Department, University of Alberta)
- 1Basarab, John (Alberta Agriculture and Rural Development)
- 1Bork, Edward (Agricultural, Food, and Nutritional Science)
- 1Bruce, Heather. L. (Agricultural, Food and Nutritional Science)
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Spring 2016
This thesis examines the cellular basis of the acute (<1 hour) anti-allodynic actions of the clinically-approved neuropathic pain drug gabapentin (GBP) in rats at the level of the spinal dorsal horn and primary somatosensory cortex. Although the clinical effectiveness of the alpha-2-delta (α2δ)...
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Fall 2022
The reason and functional relevance of why we sleep continues to perplex researchers. One fundamental reason behind why sleep remains a mystery is because it is challenging to study given how easily it is disrupted. Anesthesia has been suggested to be a model for studying sleep given the...
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Antagonistic modulation of spontaneous neural network activities in isolated newborn rat brainstem preparations by opioids and methylxanthines
DownloadFall 2012
Apnea of prematurity is a common problem among the infants born before term pregnancy. Administration of respiratory stimulating drugs methylxanthines is the most frequent therapy, often in combination with the use of intubation. Opioids are used to reduce the pain associated with intubation,...
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Fall 2010
Improving feed efficiency has become a top priority in beef cattle production because of the rapidly increasing cost of feed provision. However, because of the expense associated with collecting individual animal feed intake data, only a relatively small number of animals have been tested,...
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Application of genomics-based tools leading to the identification of markers on bovine chromosome 14 influencing milk production and carcass quality traits
DownloadFall 2009
Genetic improvements in beef and dairy cattle can bring significant advances in satisfying the global food demand, which is expected to double by 2050. Several DNA markers have been identified on bovine chromosome 14 (BTA14), but low mapping resolution prevents their refinement for identification...
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Application of manure from cattle fed with different diets affects soil properties and greenhouse gas emissions
DownloadSpring 2019
Cattle production contributes the largest portion of livestock agricultural greenhouse gas (GHG) emissions in Canada mostly in the form of methane (CH4). Efforts to reduce CH4 emissions have led to modification of diet composition for livestock, resulting in a corresponding change in manure...
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Assessment of rumen microbiota in beef heifers with different feed efficiency and managed under different feeding systems
DownloadSpring 2020
The linkage between rumen microbiota and feed efficiency has been studied in cattle managed under the drylot system, especially in the feedlot with high-grain diets. However, pasture-based beef operations still dominate the beef production system around the world. In Alberta and other provinces...
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Fall 2014
An individual’s body weight is tightly regulated by balancing food intake with energy expenditure. This is accomplished in part by secretion of the hormone leptin by adipocytes, an excess of which signals to reduce appetite and increase activity through action in the hypothalamic region of the...
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Electrophysiological and Genetic Aspects of Age-Related Macular Degeneration (AMD): Treatment Implications
DownloadFall 2014
Age-related macular degeneration (AMD) is considered a heterogeneous group of disorders. Although many genes influence susceptibility to disease, none has shown to be the primary contributor. To identify genetic contributors, distinct AMD phenotypes need to be established. We relied on...
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Spring 2012
Neuropathic pain afflicts 1.5-3% of the general population. It can be initiated by traumatic nerve injuries or diseases such as diabetic or post-herpetic neuropathy. Neuropathic pain is often initiated by abnormal spontaneous activity in sensory neurons and this provokes increased excitability of...