Search
Skip to Search Results- 103Graduate and Postdoctoral Studies (GPS), Faculty of
- 103Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 44Biological Sciences, Department of
- 41Biological Sciences, Department of/Journal Articles (Biological Sciences)
- 10Philosophy, Department of
- 8Toolkit for Grant Success
-
Carotenoid diversity in novel Hymenobacter strains isolated from Victoria Upper Glacier, Antarctica, and implications for the evolution of microbial carotenoid biosynthesis
DownloadFall 2009
Many diverse microbes have been detected in or isolated from glaciers, including novel taxa exhibiting previously unrecognized physiological properties with significant biotechnological potential. Of 29 unique phylotypes isolated from Victoria Upper Glacier, Antarctica (VUG), 12 were related to...
-
Chaperone and Gene Regulatory Roles of SMYD1b during Early Skeletal Muscle Development and Heart Morphogenesis
DownloadFall 2017
Sarcomeres are the basic contractile units that make up the striated muscle of the heart and skeletal muscle. The specification and differentiation of muscle cells and the contractile function of the sarcomere are generally well understood, but how the sarcomere assembles remains largely unknown....
-
Characterization of Human Pancreatic Beta-cell Progenitors as a Means to Alleviate the Shortage of Donor Tissue for Islet Transplantation
DownloadFall 2012
The current shortage of islet tissue from cadaveric human donors is not sustainable and will preclude islet transplantation from becoming a widespread therapeutic treatment for those with type 1 diabetes. A potential alternative source of tissue may be through isolating, expanding, and...
-
Characterizing the role of the endocannabinoid system’s catabolic enzymes FAAH and MAGL in the development of functional sensorimotor activities in zebrafish
DownloadFall 2022
The endocannabinoid system (eCS) plays a critical role in a variety of homeostatic and developmental processes. Generally, the eCS relies on the naturally produced compounds known as endocannabinoids (eCBs), which are lipophilic signaling molecules that interact with cannabinoid receptors to...
-
Collagen I: an aberrantly expressed molecule in chondrocytes or a key player in tissue stabilization and repair both in vivo and in vitro?
DownloadSpring 2010
Barley, Randall Douglas Corwyn
Extrinsic repair techniques for the treatment of acute chondral injuries continue to yield suboptimal repair. The inability of these techniques to produce hyaline cartilage underscores the limitations in our understanding of basic chondrocyte biology. Conversely, intrinsic repair tissue has not...
-
Comparative Analysis of the Anatomy of the Myxinoidea and the Ancestry of Early Vertebrate Lineages
DownloadFall 2012
The question of whether a hagfish is a true vertebrate or not has profound implications about the ancestry of the clade. New anatomical evidence allows a test of their systematic position. With dissections and serial sections of original specimens, and with a literature review, a comparative...
-
Comparative analysis of two phenotypically-similar but genomically-distinct Burkholderia cenocepacia-specific bacteriophages
Download2012
Stothard, Paul, Dennis, Jonathan J., Lynch, Karlene H.
Background Genomic analysis of bacteriophages infecting the Burkholderia cepacia complex (BCC) is an important preliminary step in the development of a phage therapy protocol for these opportunistic pathogens. The objective of this study was to characterize KL1 (vBBceSKL1) and AH2 (vBBceSAH2),...
-
Comparative genomics of Lactobacillus reuteri from sourdough reveals adaptation of an intestinal symbiont to food fermentations
Download2015
Zhao, Xin, Gänzle, Michael G., Lin, Xiaoxi B., Zheng, Jinshui
Lactobacillus reuteri is a dominant member of intestinal microbiota of vertebrates, and occurs in food fermentations. The stable presence of L. reuteri in sourdough provides the opportunity to study the adaptation of vertebrate symbionts to an extra-intestinal habitat. This study evaluated this...