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- 2Zhao, Richard
- 1Adamson, J.
- 1Alabi, Adekunle
- 1Alrabeeah, Abdollah A. M.
- 1Andermatt, Matthias
- 39Graduate and Postdoctoral Studies (GPS), Faculty of
- 39Graduate and Postdoctoral Studies (GPS), Faculty of /Theses and Dissertations
- 3Toolkit for Grant Success
- 2Agricultural, Food and Nutritional Science, Department of
- 2Agricultural, Food and Nutritional Science, Department of/Journal Articles (Agricultural, Food and Nutritional Science)
- 2Toolkit for Grant Success/Successful Grants (Toolkit for Grant Success)
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Spring 2011
Niemann-Pick Type C (NPC) disease is an autosomal recessive disorder that results in accumulation of unesterified cholesterol in late endosomes/lysosomes (LE/Ls), leading to progressive neurodegeneration and premature death. Microglia are resident immune cells of the central nervous system, which...
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Fall 2010
Concrete deep beams with small shear span-to-depth (a/d) ratios are common elements in structures. However, there are few experimental results on the behaviour of FRP reinforced concrete deep beams and no specific modelling techniques exist in design codes for such members. The objectives of this...
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Culture and Characterization of Kefir Organisms to Reproduce the Health Benefits of Traditional Kefir
DownloadSpring 2020
Fermented dairy products such as kefir have long been associated with a host of health benefits; however, the role that microbial composition has in these benefits has not been properly examined. This research aimed to examine how kefir impacts host metabolic health, as well as how alterations to...
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Developing, Implementing and Evaluating a Mental Health Training Program for Police Officers
DownloadSpring 2015
Interactions between police and individuals suffering from mental illness are very frequent. Police forces are regularly first responders to those with mental illness. Unfortunately, on occasion interactions are violent and sometimes fatal. Despite this, training police how to best interact with...
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Dietary oxysterols are incorporated in plasma triglyceride rich lipoproteins, increase their susceptibility to oxidation and increase aortic cholesterol concentration of rabbits
Download1998
Mamo, John C. L., Croft, Kevin D., Vine, Donna F., Mori, Tetsuya, Beilin, Lawrence J.
Early fatty streaks and advanced lesions are characterized by the deposition of cholesterol and cholesterol oxidation products (oxysterols). Oxysterols have been shown to be cytotoxic and pro-atherogenic compared to cholesterol and are found in cholesterol-rich processed foods. The consumption of...
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Spring 2015
Cholesterol is well known for its adverse cardiovascular effects, however it has crucial cellular roles. For instance, cholesterol is a key component of eukaryotic cell membranes and constitutes the principle steroid hormone precursor in most animals. Cellular cholesterol concentrations have to...
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Spring 2015
Personality has been documented in diverse taxa and growing attention is being directed towards the ecological implications of consistent variation in individual behaviour. These implications include the rise in habituation behaviour by wildlife living in human-disturbed areas, which has resulted...
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Effect of Cholesterol Accumulation on the Metabolism of Amyloid Precursor Protein (APP) in Cultured N2a Cells
DownloadFall 2015
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder believed to be triggered by the accumulation of β-amyloid (Aβ) peptides derived from the proteolytic processing of amyloid precursor protein (APP). Accumulated evidence has shown that alterations in the levels and/or subcellular...