Search
Skip to Search Results- 56Inflammation
- 43Bacteria
- 25Microbiome
- 17Chemotherapy
- 12Gastrointestinal Tract
- 6Clostridium difficile
- 6Gänzle, Michael G.
- 5Willing, Benjamin P.
- 4Finlay, B. Brett
- 3Chakrabarti, Subhadeep
- 3Field, Catherine J.
- 3Koleva, Petya
- 77Graduate and Postdoctoral Studies (GPS), Faculty of
- 77Graduate and Postdoctoral Studies (GPS), Faculty of /Theses and Dissertations
- 30Agricultural, Food and Nutritional Science, Department of
- 30Agricultural, Food and Nutritional Science, Department of/Journal Articles (Agricultural, Food and Nutritional Science)
- 6Biological Sciences, Department of
- 5Medicine and Dentistry, Faculty of
-
A characterization of inflammatory and structural markers within the rumen epithelium during grain-induced ruminal acidosis in lactating dairy cattle
Download2012
Steele, Michael A., Plaizier, Jan C., AlZahal, Ousama, Dionissopoulos, Louis, McBride, Brian W.
The objective of this study was to characterize the mRNA and protein expression of inflammatory and structural genes in the rumen epithelium during grain-induced ruminal acidosis in lactating dairy cattle. A total of 16 rumen-fistulated, lactating Holstein dairy cattle (618±35 kg of body weight,...
-
A mechanistic model of intermittent gastric emptying and glucose-insulin dynamics following a meal containing milk components
Download2016
Cant, John P., Steele, Michael A., Stahel, Priska, MacPherson, Jayden A. R., Berends, Harma
To support decision-making around diet selection choices to manage glycemia following a meal, a novel mechanistic model of intermittent gastric emptying and plasma glucose-insulin dynamics was developed. Model development was guided by postprandial timecourses of plasma glucose, insulin and the...
-
A Novel Comparative Analysis Approach to Personalize Chemotherapy Dose Calculation in Early Breast Cancer
DownloadFall 2018
Background Worldwide, body surface area [BSA] is used to calculate chemotherapy dose. The BSA formula was originally developed in 1916, derived from height and weight, with no consideration of other patient characteristics. Most chemotherapy agents have a narrow therapeutic index and are...
-
A preliminary study of chemical and microbial characteristics of the Athabasca River in the Athabasca oil sands area of northeastern Alberta
Download1979
Costerton, J. W., Nix, P. G., Ventullo, R., Coutts, R. T.
A literature review and evaluation of methods used to determine rates of bacterial uptake (heterotrophic assimilation) of organic substrates in fresh water systems was undertaken. The uptake of a \"universal\" substrate - radiolabelled glutamic acid - was determined in order to assess the effects...
-
Fall 2011
This study determined how chemotherapy treatment for colorectal cancer alters hepatic fat metabolism. Livers were isolated from tumor-bearing animals after one and two cycles of chemotherapy consisting of irinotecan plus 5-fluorouracil. Fatty acid amounts and composition within triglycerides (TG)...
-
Altered ganglioside metabolism in inflammatory bowel disease and the impact of dietary ganglioside intake
DownloadFall 2014
Gangliosides are integral to the structure and function of the plasma membrane. Ganglioside composition of the small intestinal brush border membrane and apical surface of the colon influence numerous cell processes including microbial attachment, cell division, differentiation, and signaling....
-
2011
Willing, Benjamin P., Finlay, B. Brett , Thanachayanont, Teerawat, Croxen, Matthew, Vacharaksa, Anjalee
Host resistance to bacterial infections is thought to be dictated by host genetic factors. Infections by the natural murine enteric pathogen Citrobacter rodentium (used as a model of human enteropathogenic and enterohaemorrhagic E. coli infections) vary between mice strains, from mild...
-
An alternative physiological role for the EmhABC efflux pump in Pseudomonas fluorescens cLP6a
Download2011
Background Efflux pumps belonging to the resistance-nodulation-division (RND) superfamily in bacteria are involved in antibiotic resistance and solvent tolerance but have an unknown physiological role. EmhABC, a RND-type efflux pump in Pseudomonas fluorescens strain cLP6a, extrudes hydrophobic...