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Skip to Search Results- 3Force spectroscopy
- 3Protein misfolding
- 2Biophysics
- 2Optical tweezers
- 2Prion protein
- 2Protein folding
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Atomic Force Microscopy Characterization of Hydrogen Terminated Silicon (100) 2x1 Reconstruction
DownloadFall 2015
Non-contact Atomic Force Microscopy (NC-AFM) is a Scanning Probe Microscopy tool offering unique non-perturbative analysis of surfaces and adsorbates at the atomic scale. AFM precisely oscillates a sharp tip above a sample. By monitoring the shift in resonance frequency of a quartz tuning fork...
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Fall 2014
Intrinsically disordered proteins (IDPs) represent a large subpopulation of the proteome, and are characterized by high structural plasticity and a predisposition to aggregate. These aggregates can accumulate inside or outside the cell, often forming amyloid plaques that are implicated in a...
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Fall 2013
Protein folding involves a stochastic search through the configurational energy landscape towards the native structure. Although most proteins have evolved to fold efficiently into a unique native structure, misfolding (the formation of non-native structures) occurs frequently in vivo causing a...
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Fall 2017
The formation of an abnormal form of proteins in cells can cause aggregation and neurodegenerative pathology, such as Alzheimer’s, Parkinson’s and prion diseases, which affects both humans and animals. Nowadays, the understanding of the mechanism of prion misfolding and propagation, including...