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Skip to Search Results- 13Cryopreservation
- 9Articular cartilage
- 7Vitrification
- 4Chondrocytes
- 4Viability
- 3Cryoprotectant agents
- 11Chemical and Materials Engineering, Department of
- 11Chemical and Materials Engineering, Department of/Research Articles and Materials (Chemical and Materials Engineering)
- 11Graduate and Postdoctoral Studies (GPS), Faculty of
- 11Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 7Surgery, Department of
- 7Surgery, Department of/Orthopaedic Surgery
- 3Department of Chemical and Materials Engineering
- 3Department of Surgery
- 1Department of Civil and Environmental Engineering
- 1Department of Mathematical and Statistical Sciences
- 1Department of Physical Therapy
- 1Department of Renewable Resources
- 1Adesida, Adetola (Surgery)
- 1Adesida, Adetola B. (Surgery)
- 1Bagnall, Keith (Department of Surgery)
- 1Boluk, Yaman (Civil and Environmental Engineering)
- 1Elliott, Janet A. W. (Chemical & Materials Engineering and Laboratory Medicine & Pathology)
- 1Elliott, Janet A.W. (Chemical and Materials Engineering)
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Investigating cryoinjury using simulations and experiments: 1. TF-1 cells during two-step freezing (rapid cooling interrupted with a hold time)
Download2014-09-22
McGann, L. E., Ross-Rodriguez, L. U., Elliott, J. A.
There is significant interest in designing a cryopreservation protocol for hematopoietic stem cells (HSC) which does not rely on dimethyl sulfoxide (Me2SO) as a cryoprotectant. Computer simulations that describe cellular osmotic responses during cooling and warming can be used to optimize the...
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Linking occurrence and fitness to persistence: habitat-based approach for endangered greater sage-grouse
Download2007
Detailed empirical models predicting both species occurrence and fitness across a landscape are necessary to understand processes related to population persistence. Failure to consider both occurrence and fitness may result in incorrect assessments of habitat importance leading to inappropriate...
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Modeling the transport of cryoprotective agents in articular cartilage for cryopreservation
DownloadSpring 2011
Loading vitrifiable concentrations of cryoprotective agents is an important step for cryopreservation of biological tissues by vitrification for research and transplantation purposes. This may be done by immersing the tissue in a cryoprotective agent (CPA) solution, and increasing the...
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Spring 2013
A major barrier to reclamation after oil sands mining is lack of commercially available, diverse native plant seeds and propagules for revegetation. Potential of LFH (forest floor material) developed on coarse textured soil for establishing native plants and how salvage, placement and storage...
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Fall 2015
Osteoarthritis, a disease resulting in the breakdown of cartilage and bone within joints, is a global burden that is growing in scope. There is no cure for osteoarthritis, and the current treatments are all lacking in some form or another. One treatment which attempts to prevent degeneration of...
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2014-09-26
Rekieh, K., Abazari, A., Elliott, J.A., Jomha, N.M., Law, G.K., McGann, L.E.
Objective: Osteochondral allografting is an effective method to treat large osteochondral defects but difficulties in tissue preservation have significantly limited the application of this technique. Successful cryopreservation of articular cartilage (AC) could improve the clinical availability...
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Fall 2015
Cryopreserving cells for human health therapeutics is a multidisciplinary process with great complexity. Cryopreservation of human umbilical vein endothelial cells (HUVECs) has facilitated vascular biology research since they were first isolated in 1973 [59]; however identifying key variables to...
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Fall 2016
Articular cartilage injury is a major risk factor for the development of osteoarthritis, a condition that results in significant patient morbidity and substantial cost to the healthcare system. Due to the limited capacity of articular cartilage to regenerate, early intervention is required to...
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Statistical prediction of the vitrifiability and glass stability of multi-component cryoprotective agent solutions.
Download2010
Forbes, J. F., Law, G. K., Weiss, A. D., Scheuerman, A., McGann, L. E., Elliott, J. A., Jomha, N. M.
Long-term biologic storage of articular cartilage has proven elusive due to cellular degradation over time or acute damage during attempts at cryopreservation. Vitrification is one option that may result in successful cryopreservation but difficulty with cryoprotective agent (CPA) toxicity at...