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Invited major book review of M. Cannon & L. Sunseri, (2011), “Racism, Colonialism, and Indigeneity in Canada: A Reader”
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Book Review: Racism, Colonialism, and Indigeneity in Canada: A Reader, Edited by Martin J. Cannon and Lina Sunseri. Toronto: Oxford University Press Canada, 2011, paperback, 284 pages. ISBN 978-0-1954-3231-2
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Characterization of the cold stress-induced cyanobacterial DEAD-box protein CrhC as an RNA helicase
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Owttrim, George W., Yu, Esther
We have shown previously that CrhC is a unique member of the DEAD-box family of RNA helicases whose expression occurs specifically under conditions of cold stress. Here we show that recombinant His-tagged CrhC, purified from Escherichia coli, is an ATP-independent RNA binding protein possessing...
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Fall 2024
Viral diseases are a constant threat that have profound impact on global health, economics and societies. Understanding virus-host interactions is key for advancing our knowledge of viral replication and pathogenesis, and thus for the development of effective antiviral strategies to better...
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Treatment of Antiviral Drugs in Wastewater Using Advanced Oxidation Processes - Ozonation of Oseltamivir Phosphate
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While wastewater treatment facilities are designed to remove contaminants from water before it returns to the environment, unfortunately, not all of these facilities are effective in the removal of micropollutants (MPs). Antiviral drugs are a class of MPs that have become an area of concern due...
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Fall 2021
Poxviruses encode many genes that are orthologs of cellular genes. These orthologs serve many functions, but those that are of most interest are ones that have evolved further and now serve an immune-evasion function. Such genes were likely first acquired by poxviruses through some form of...
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Fall 2017
Most antivirals target viral proteins and are specific for only one virus, or even one viral genotype. Whereas viral proteins are encoded in the plastic viral genome, virion lipids are not and their rearrangements during fusion of the virion envelope to cellular membranes are conserved among...
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Fall 2020
Infectious respiratory diseases, caused by viruses and bacteria that attack the respiratory system, constitute a serious threat in public health around the world. Pathogens can be transmitted in the air though large droplets or aerosols. As aerosols can linger in the environment for a prolonged...
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Spring 2014
This thesis examines the pathophysiology of asthma, attempts to determine the cellular mechanisms behind viral-induced immune memory mediated asthma exacerbations, and investigates urinary metabolomic biomarkers of asthma and neonatal hypoxia.