Search
Skip to Search Results- 1Adam, Ibrahim S. Y.
- 1Aguda, R. M.
- 1Alford, Spencer Caleb
- 1Anbukarasu, Preetam
- 1Arutyunov, Denis
- 1Assempour, Nazanin
-
Fall 2009
Islet transplantation has the potential to be an effective treatment for patients with type 1 diabetes. However, a shortage of human donor islets and the need for continuous immunosuppressive therapy currently limit this therapy to patients with brittle type 1 diabetes. Neonatal pigs may...
-
Nanophotonic detection of nanomechanical structures for use toward mass sensing applications
DownloadSpring 2014
Nanomechanical beam resonators show much promise for use in integrated on-chip mass sensing systems. This follows from their own very small masses and also their ability to store the mechanical energy of their oscillations to produce strong measurable mechanical response signals. To achieve...
-
Fall 2016
Background: NK cells are a key cellular component of antibody-mediated rejection (ABMR), but their role in ABMR has not been identified. We postulated that NK cells are stimulated through their CD16a antibody receptors by donor-specific anti-HLA antibodies in ABMR. There is currently no direct...
-
Fall 2016
The field of conducting polymers and mainly organic electrochemical transistors (OECT) have been investigated for bioelectronics applications. Advantages such as conformability, high quality electrical contact, ease of fabrication and biocompatibility made OECTs a great potential of future bio...
-
Fall 2018
Ghoraishi Kahangi, Maryam Sadat
Due to their ability to measure extremely small displacements and forces, nanomechanical cantilevers have attracted considerable attention from numerous scientific communities, each exploring a variety of applications. Though typically operated in either vacuum or air, operation of the device in...
-
Spring 2011
Several obstacles to widespread use of bacteriocins in food have been identified, including lack of specific, rapid quantitation methods, and little data on their efficacy in food systems. The first objective of this study was to develop a specific, rapid quantitation method for bacteriocins...
-
Fall 2009
Microcantilever sensor has gained much popularity because of its high sensitivity and selectivity. It consists of a micro-sized cantilever that is usually coated on one side with chemical/biological probe agents to generate strong attraction to target molecules. The interactions between the probe...
-
Specific detection of Campylobacter jejuni using the bacteriophage NCTC 12673 receptor binding protein as a probe
Download2011
Szymanski, Christine M., Arutyunov, Denis, McDermott, Mark T., Evoy, Stephane, Singh, Amit
Campylobacter jejuni is found in the intestines of poultry, cattle, swine, wild birds and pet animals and is the major cause of foodborne gastroenteritis in developed countries. We report the use of the receptor binding protein (RBP) of Campylobacter bacteriophage NCTC 12673 for the specific...
-
Fall 2009
Resonant microcantilevers are promising transducers for bacteria detection because of their high sensitivities. Surface stress and mass from adsorbates affect the resonant frequency. We developed a novel method for decoupling the frequency contributions of a change in mass and surface stress on a...
-
Study of Non-Covalent Protein-Carbohydrate Interactions by Nanoelectrospray Ionization Mass Spectrometry and Surface Plasmon Resonance
DownloadFall 2015
This thesis describes the application of electrospray ionization mass spectrometry (ESI-MS) techniques to identify and quantify antibody-antigen interactions in vitro. Also potential application of nanodiscs (ND) as membrane model in ESI-MS and surface plasmon resonance (SPR) spectroscopy has...