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Skip to Search Results- 27Villatoro, Valentin (Supervisor)
- 22Fraser, Marion
- 5To, Michelle
- 3Kwon, Gloria
- 2Aguzzi, Adriano
- 2Ametaj, Burim N.
- 27Medicine and Dentistry, Faculty of
- 27Medicine and Dentistry, Faculty of/Medical Laboratory Science, Division of
- 8Graduate and Postdoctoral Studies (GPS), Faculty of
- 8Graduate and Postdoctoral Studies (GPS), Faculty of /Theses and Dissertations
- 4Agricultural, Food and Nutritional Science, Department of
- 4Agricultural, Food and Nutritional Science, Department of/Journal Articles (Agricultural, Food and Nutritional Science)
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Anti-Malarial Strategies Among Vulnerable Populations: exploring bed net underutilization among internally displaced persons and novel adjunctive therapies for cerebral malaria
DownloadFall 2017
Background: Despite declining incidence globally, malaria morbidity and mortality remain elevated among internally displaced persons (IDPs) and children under five, particularly in sub-Saharan Africa. Malaria prevention and treatment efforts in the Democratic Republic of the Congo (DRC) are...
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Clinical impact of submicroscopic malaria on delivery outcomes and the role of VAR2CSA antibodies in pregnant women from Colombia
DownloadFall 2018
Malaria caused by the genus Plasmodium (P.) is one of the oldest and most important parasitic infections globally. Pregnant women are at an increased risk for malaria, where the disease poses a significant risk to both maternal and child health. Better diagnosis of malaria can have an immediate...
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Crystallization and preliminary X-ray diffraction analysis of prion protein bound to the Fab fragment of the POM1 antibody
Download2011
James, Michael N. G., Swayampakula, Mridula , Polymenidou, Magdalini , Kav, Nat N. V., Aguzzi, Adriano, Wieland, Barbara, Baral, Pravas K.
Prion diseases are neurodegenerative diseases that are characterized by the conversion of the cellular prion protein PrPc to the pathogenic isoform PrPsc. Several antibodies are known to interact with the cellular prion protein and to inhibit this transition. An antibody Fab fragment, Fab POM1,...
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Intravaginal lactic acid bacteria modulated local and systemic immune responses and lowered the incidence of uterine infections in periparturient dairy cows
Download2015
Dunn, Suzanna M., Odhiambo, John F., Farooq, Umar, Ametaj, Burim N., Lam, Tran, Deng, Qilan
The objective of this investigation was to evaluate whether intravaginal infusion of a lactic acid bacteria (LAB) cocktail around parturition could influence the immune response, incidence rate of uterine infections, and the overall health status of periparturient dairy cows. One hundred pregnant...
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Investigation of antibody-mediated immune mechanisms during submicroscopic infections of pregnancy-associated malaria in pregnant women from Colombia
DownloadFall 2021
Malaria has been a threat to humans for centuries and continues to be a global health problem. Repeated exposure to malaria in childhood can result in protective immunity that reduces parasite invasion of red blood cells and the sequestration of infected red blood cells (iRBC) in the tissues....
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Investigation of the immunological cross-reactivity between Plasmodium vivax Duffy Binding Protein and Plasmodium falciparum VAR2CSA for vaccine development
DownloadFall 2021
Worldwide, an estimated 30 million pregnancies are at risk of malaria infection each year. In pregnancy, Plasmodium falciparum parasites express a protein called VAR2CSA that mediates adherence of infected red blood cells (iRBCs) to chondroitin sulfate A (CSA) in the placenta. VAR2CSA antibodies...
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Investigation of the Molecular Mechanisms That Determine Isolate-Specific, Antibody-Mediated Neutralization of HCV infectivity
DownloadFall 2018
It is estimated that there are about 1.75 million new Hepatitis C Virus (HCV) infections per year worldwide and around 20% will develop liver cirrhosis or liver cancer if left untreated. Direct acting antiviral drugs are available for the treatment of HCV with success rates of over 90%. But...