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Skip to Search Results- 25Graduate and Postdoctoral Studies (GPS), Faculty of
- 25Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 20Biological Sciences, Department of
- 20Biological Sciences, Department of/Journal Articles (Biological Sciences)
- 6Agricultural, Food and Nutritional Science, Department of
- 6Agricultural, Food and Nutritional Science, Department of/Journal Articles (Agricultural, Food and Nutritional Science)
- 34Article (Published)
- 25Thesis
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Molecular cloning of cDNA encoding a 55-kDa multifunctional thyroid hormone binding protein of skeletal muscle sarcoplasmic reticulum
Download1990-01-01
Fliegel, Larry, Newton, E., Burns, K., Michalak, M.
A cDNA clone encoding 55-kDa multifunctional, thyroid hormone binding protein of rabbit skeletal muscle sarcoplasmic reticulum was isolated and sequenced. The cDNA encoded a protein of 509 amino acids, and a comparison of the deduced amino acid sequence with the NH2-terminal amino acid sequence...
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Molecular Dynamics Simulations of Polyethylenimine Mediated Nucleic Acid Complexation with Implications for Non-viral Gene Delivery
DownloadSpring 2013
Gene therapy is a promising therapeutic technique that involves delivering nucleic acids into cells. Polycations have evolved into a major category of gene carriers. Polyethylenimine (PEI) is one of the most effective polycationic carriers. Furthermore, modifying PEI with certain lipophilic...
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Spring 2016
Hybrids formed by biological entities and human-made nano-structures have been intensively studied in recent years due to their very interesting properties and applications. DNA-carbon nanotube (CNT) hybrid is one such material and the motivation of this PhD study. The interaction of DNA building...
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PA-GOSUB: A searchable database of model organism protein sequences with their predicted GO molecular function and subcellular localization
Download2005
Poulin, B., Lu, P., Wishart, D.S., Szafron, D., Lamb, N., Eisner, R., Pearcy, B., Ngo, D., Fyshe, A., Grenier, R.
PA-GOSUB (Proteome Analyst: Gene Ontology Molecular Function and Subcellular Localization) is a publicly available, web-based, searchable and downloadable database that contains the sequences, predicted GO molecular functions and predicted subcellular localizations of more than 107 000 proteins...
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PCR-based methods for identification of two Eteobalea species (Lepidoptera: Cosmopterigidae) used as biocontrol agents of weedy Linaria species (Scrophulariaceae)
Download2005
Pohl, G. R., McClay, A. S., Sperling, F. A. H., Mitchell, A.
Two European species of the genus Eleobalea Hodges are being tested as classical biological control agents for toadflax (Linaria spp.) in Canada. Permits for the release of these species apply only to an Italian population of E. serratella Treitschke and a Serbian population of E. intermediella...
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PolySearch: A web-based text mining system for extracting relationships between human diseases, genes, mutations, drugs and metabolites
Download2008
Stothard, P., Damaraju, S., Wishart, D.S., Young, N., Cheng, D., Knox, C.
A particular challenge in biomedical text mining is to find ways of handling ‘comprehensive’ or ‘associative’ queries such as ‘Find all genes associated with breast cancer’. Given that many queries in genomics, proteomics or metabolomics involve these kind of comprehensive searches we believe...
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PolySearch: A web-based text mining system for extracting relationships between human diseases, genes, mutations, drugs and metabolites
Download2008
Cheng, Dean, Stothard, Paul, Damaraju, Sambasivarao, Wishart, David S., Knox, Craig, Young, Nelson
A particular challenge in biomedical text mining is to find ways of handling ‘comprehensive’ or ‘associative’ queries such as ‘Find all genes associated with breast cancer’. Given that many queries in genomics, proteomics or metabolomics involve these kind of comprehensive searches we believe...
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Spring 2022
The DNA damage response (DDR) is critical for maintaining genomic integrity and prevention of genotoxic consequences leading to carcinogenesis. The DDR signaling cascade results either in the activation of the repair pathway, or initiation of apoptosis if the repair is not possible. Many...