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Skip to Search Results- 1Abdrabou, Abdalla
- 1Aulakh, Amit
- 1Backs, Jonathan A.J.
- 1Baedke, Jessica
- 1Bai, Xuechun
- 1Bosnjak, Natasa
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Spring 2017
Cannabis use is a known risk factor for the development of psychotic disorders. Clinical and preclinical genetic studies provide growing evidence that genes related to dopamine signalling and neuroprotection, like COMT, are implicated in the cannabis-psychosis association. Considering the burden...
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Advanced agronomic practices to maximize feed barley (Hordeum vulgare L.) yield, quality, and standability in Alberta environments
DownloadFall 2017
The grain yields of feed barley (Hordeum vulgare L.) have increased at a slower rate than the yields of other major crops in Alberta, and seeded barley acres have declined over the past 20 years. Agronomic management and cultivar specific responses to management may provide solutions to increase...
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Anti-Cancer Mechanism of Trastuzumab via Blocking Nuclear HER2 Function and Epigenetic Mechanism of Resistance
DownloadSpring 2020
HER2 receptor tyrosine kinase (encoded by ERBB2 gene) is overexpressed in approximately 25% of all breast cancer tumors (known as HER2-positive breast cancers). Overexpression of HER2 causes overactivation of downstream receptor tyrosine kinase pathways including PI3K/Akt and MAPK pathways and is...
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Fall 2010
Improving feed efficiency has become a top priority in beef cattle production because of the rapidly increasing cost of feed provision. However, because of the expense associated with collecting individual animal feed intake data, only a relatively small number of animals have been tested,...
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Application of genomics-based tools leading to the identification of markers on bovine chromosome 14 influencing milk production and carcass quality traits
DownloadFall 2009
Genetic improvements in beef and dairy cattle can bring significant advances in satisfying the global food demand, which is expected to double by 2050. Several DNA markers have been identified on bovine chromosome 14 (BTA14), but low mapping resolution prevents their refinement for identification...
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Contribution to the taxonomy of Oxytropis campestris (L.) DC. in northwestern North America
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Masters thesis. Suggests elevation of five taxa of Oxytropis campestris to species status, based on chromosome studies.
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Fall 2014
An individual’s body weight is tightly regulated by balancing food intake with energy expenditure. This is accomplished in part by secretion of the hormone leptin by adipocytes, an excess of which signals to reduce appetite and increase activity through action in the hypothalamic region of the...
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Electrophysiological and Genetic Aspects of Age-Related Macular Degeneration (AMD): Treatment Implications
DownloadFall 2014
Age-related macular degeneration (AMD) is considered a heterogeneous group of disorders. Although many genes influence susceptibility to disease, none has shown to be the primary contributor. To identify genetic contributors, distinct AMD phenotypes need to be established. We relied on...
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Spring 2017
Pulses of ecdysone, a steroid hormone, play an integral role during insect development however, how these ecdysone pulses are regulated has been relatively unexplored. I have shown that the presence of nitric oxide (NO) within the larval prothoracic gland (PG), the principal source of larval...
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Fall 2021
Disease resilience is defined as an animal’s ability to maintain a high level of performance in the face of disease challenges caused by multiple pathogens, as is often the case in commercial pig farms. Therefore, disease resilience is anticipated to be critical to the profitability of the pig...