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Skip to Search Results- 1Abdrabou, Abdalla
- 1Aulakh, Amit
- 1Baedke, Jessica
- 1Bai, Xuechun
- 1Bosnjak, Natasa
- 1Burke, Lindsey Alison
- 7Medical Sciences-Medical Genetics
- 5Department of Biological Sciences
- 4Department of Agricultural, Food, and Nutritional Science
- 3Neuroscience
- 2Department of Agricultural, Food and Nutritional Science
- 1Department of Botany
- 2Wang, Zhixiang (Medical Genetics)
- 1Aitchison, Katherine (Psychiatry)
- 1Basarab, John (Alberta Agriculture and Rural Development)
- 1Berry, Fred (Surgery)
- 1Changxi Li (Agricultural, Food, and Nutritional Science)
- 1Clayton T. Dickson (Psychology, Physiology, Anesthesia and Pain Medicine, Neuroscience and Mental Health Institute)
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Spring 2017
Cannabis use is a known risk factor for the development of psychotic disorders. Clinical and preclinical genetic studies provide growing evidence that genes related to dopamine signalling and neuroprotection, like COMT, are implicated in the cannabis-psychosis association. Considering the burden...
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Fall 2022
The reason and functional relevance of why we sleep continues to perplex researchers. One fundamental reason behind why sleep remains a mystery is because it is challenging to study given how easily it is disrupted. Anesthesia has been suggested to be a model for studying sleep given the...
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Advanced agronomic practices to maximize feed barley (Hordeum vulgare L.) yield, quality, and standability in Alberta environments
DownloadFall 2017
The grain yields of feed barley (Hordeum vulgare L.) have increased at a slower rate than the yields of other major crops in Alberta, and seeded barley acres have declined over the past 20 years. Agronomic management and cultivar specific responses to management may provide solutions to increase...
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Anesthesia and the Aging Vasculature: Effects of Propofol on Hemodynamics and Vascular Function
DownloadSpring 2014
An increasing life expectancy in Canada has resulted in increasing proportions of elderly patients requiring anesthetic care for surgical procedures. Aging is associated with cardiovascular changes resulting in increased vasoconstriction and hypertension, and medications such as angiotensin...
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Anti-Cancer Mechanism of Trastuzumab via Blocking Nuclear HER2 Function and Epigenetic Mechanism of Resistance
DownloadSpring 2020
HER2 receptor tyrosine kinase (encoded by ERBB2 gene) is overexpressed in approximately 25% of all breast cancer tumors (known as HER2-positive breast cancers). Overexpression of HER2 causes overactivation of downstream receptor tyrosine kinase pathways including PI3K/Akt and MAPK pathways and is...
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Fall 2010
Improving feed efficiency has become a top priority in beef cattle production because of the rapidly increasing cost of feed provision. However, because of the expense associated with collecting individual animal feed intake data, only a relatively small number of animals have been tested,...
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Application of genomics-based tools leading to the identification of markers on bovine chromosome 14 influencing milk production and carcass quality traits
DownloadFall 2009
Genetic improvements in beef and dairy cattle can bring significant advances in satisfying the global food demand, which is expected to double by 2050. Several DNA markers have been identified on bovine chromosome 14 (BTA14), but low mapping resolution prevents their refinement for identification...
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Contribution to the taxonomy of Oxytropis campestris (L.) DC. in northwestern North America
Download1978
Masters thesis. Suggests elevation of five taxa of Oxytropis campestris to species status, based on chromosome studies.
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Fall 2014
An individual’s body weight is tightly regulated by balancing food intake with energy expenditure. This is accomplished in part by secretion of the hormone leptin by adipocytes, an excess of which signals to reduce appetite and increase activity through action in the hypothalamic region of the...
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Electrophysiological and Genetic Aspects of Age-Related Macular Degeneration (AMD): Treatment Implications
DownloadFall 2014
Age-related macular degeneration (AMD) is considered a heterogeneous group of disorders. Although many genes influence susceptibility to disease, none has shown to be the primary contributor. To identify genetic contributors, distinct AMD phenotypes need to be established. We relied on...