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Skip to Search Results- 31Graduate and Postdoctoral Studies (GPS), Faculty of
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- 5Department of Chemistry
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- 2Faculty of Nursing
- 1Dentistry
- 2Kurgan, Lukasz (Electrical and Computer Engineering)
- 1Adamowicz, Vic (Resource Economics and Environmental Sociology)
- 1Ball, Ronald O. (Department of Agricultural, Food and Nutritional Science)
- 1Ballermann, Barbara (Medicine)
- 1Boekhoven, Job (Chemistry, Technical University of Munich)
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Screening anti-cancer drugs against tubulin using catch-and-release electrospray ionization mass spectrometry
Download2016
Kitova, Elena N., Klassen, John S., Winter, Philip, Tuszynski, Jack A., Darestani, Reza R.
Tubulin, which is the building block of microtubules, plays an important role in cell division. This critical role makes tubulin an attractive target for the development of chemotherapeutic drugs to treat cancer. Currently, there is no general binding assay for tubulin–drug interactions. The...
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Screening anti-cancer drugs against tubulin using catch-and-release electrospray ionization mass spectrometry
Download2016
Kitova, Elena N., Klassen, John S., Winter, Philip, Tuszynski, Jack A., Darestani, Reza R.
Tubulin, which is the building block of microtubules, plays an important role in cell division. This critical role makes tubulin an attractive target for the development of chemotherapeutic drugs to treat cancer. Currently, there is no general binding assay for tubulin–drug interactions. The...
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2012-10-12
SSHRC Awarded IG 2013: This research program will explore Michel Foucault's influential work on sexuality and delinquency. The three-fold objectives of this research program are: first, to take up Foucault’s genealogical studies of delinquency and sexuality in order to pursue a more sustained and...
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Simultaneous measurement of protein and energy metabolism and application to determine lysine requirements in sows
DownloadSpring 2011
Simultaneous measurements of energy and protein metabolism can provide valuable information about their interactions. Dietary lysine is limiting in typical feedstuffs fed to swine and, therefore, limits protein synthesis. Current recommendations for dietary amino acid and energy intakes may not...
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2016-10-11
SSHRC Awarded IG 2017: This project aims to change the way we think about sleep as well as the way we practice it. It communicates to diverse audiences that sleep is not a mysterious non-experience (essential but a wasteful interruption of life) but rather a central part of existence that tells...
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2011-10-10
SSHRC Awarded IG 2012: This study will generate robust data on the social disadvantage and subjective well-being of Canadian children and youth with disabilities. The study has three objectives. 1] determine the nature and level of social disadvantage faced by young Canadians with disabilities...
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Structure and dynamics of biomolecules: probing muscle regulation, prion protein unfolding, and drug insertion into DNA by nuclear magnetic resonance spectroscopy
DownloadSpring 2011
Nuclear magnetic resonance (NMR) spectroscopy is a powerful approach to study the structure and dynamics of macromolecules in a close-to-native solution environment. In the present thesis I present my investigation of protein and nucleic acid structure and dynamics in a wide variety of biological...
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2015-12-01
SSHRC Awarded PDG 2016: This study aims to determine a solution to two inter-related problems for human services in Quebec and Alberta. One problem is that we currently lack the requisite knowledge to 'make good' on our commitment under the United Nations Convention on the Rights of Persons with...
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The APETALA-2-Like Transcription Factor OsAP2-39 Controls Key Interactions between Abscisic Acid and Gibberellin in Rice
Download2010
Rothstein, Steven J., Bi, Yong-Mei, Zhu, Tong, El-kereamy, Ashraf, Beatty, Perrin H., Yaish, Mahmoud W., Good, Allen G.
The interaction between phytohormones is an important mechanism which controls growth and developmental processes in plants. Deciphering these interactions is a crucial step in helping to develop crops with enhanced yield and resistance to environmental stresses. Controlling the expression level...