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Skip to Search Results- 2Currie, Cheryl
- 1Alzaben, Abeer Salman
- 1Ansion, Mariel
- 1Avni, Anoosha E.
- 1Bryans, David Garth.
- 1Chaudhuri, Sheel
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Social Determinants of Alcohol, Drug and Gambling Problems Among Urban Aboriginal Adults in Canada
DownloadSpring 2012
Objective: Little is known about the determinants of addictive disorders within the rapidly growing urban Aboriginal population in Canada. The objectives of this dissertation were to examine whether racial discrimination, Aboriginal enculturation, and Canadian acculturation were associated with...
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The prevalence and determinants of adequate vitamin D intake and supplementation among Canadian children
DownloadFall 2016
Most Canadian children are not meeting the dietary recommendations for vitamin D and have not enough sun exposure to synthesize vitamin D in their skin. Vitamin D supplementation therefore seems a necessity. However, no study has examined whether vitamin D from diet and supplements combined is...
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The Role of Vitamin D in Anti-Tumor Necrosis Factor-Alpha-Induced Response in Patients with Inflammatory Bowel Disease
DownloadFall 2014
Vitamin D is an important immunomodulator of the immune system and has been suggested to play a role in the pathogenesis of inflammatory bowel disease (IBD). Drugs targeting TNF-alpha are effective IBD therapies, and vitamin D has been demonstrated to suppress TNF-alpha as well as work...
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Understanding the role of Clostridioides difficile and Vitamin D supplementation in shaping the gut microbiome of Canadian infants
DownloadSpring 2019
Introduction: The gut microbiome is shaped during infancy and has an important role in the development of both the immune and metabolic systems. Many early life exposures and events contribute to the composition of this complex intestinal environment, notably early infant diet and breastfeeding....
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Vitamin D Status and Markers of Cardiometabolic and Liver Disease Risk in Childhood Obesity
DownloadSpring 2017
Vitamin D insufficiency is highly prevalent in children (up to 40%), particularly in northern climates such as Alberta, due to reduced sunlight exposure and low intake. Although suboptimal vitamin D status and metabolic dysregulation are commonly observed in obesity, little is known about the...
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Vitamin D Supplementation and Bone Health in Adults with Diabetic Nephropathy: Preliminary Findings from a Randomized Controlled Trial
DownloadFall 2013
Vitamin D (vitD) is a nutrient of concern in Canada particularly for those with diabetes and chronic kidney disease (CKD). Participants (18-80y) with diabetes and CKD were randomized to receive either 50mcg/day (n=33) or 1,000mcg/month (n=30) vitD3 for 6-months. Variables studied included:...
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Fall 2014
Epidemiological studies correlate vitamin D deficiency with asthma severity. Calcitriol modulates receptor and cytokine expression from various leukocytes in an anti-inflammatory manner. Despite eosinophil activity during mucosal inflammation, knowledge on the direct effect of calcitriol on this...