Search
Skip to Search Results- 1Abdulsalam Alharbi
- 1Aktary, Zackie M
- 1Alolayan, Waad Riyad
- 1Alshamsan, Aws
- 1Alyenbaawi, Hadeel Eb
- 1Amritpal Singh Bhullar
- 11Department of Oncology
- 7Faculty of Pharmacy and Pharmaceutical Sciences
- 6Department of Agricultural, Food, and Nutritional Science
- 5Department of Biochemistry
- 4Faculty of Nursing
- 4Faculty of Rehabilitation Medicine
- 3Lavasanifar, Afsaneh (Faculty of Pharmacy and Pharmaceutical Sciences)
- 3Uludag, Hasan (Chemical and Materials Engineering)
- 2Damaraju, Sambasivarao (Laboratory Medicine and Pathology)
- 2Hitt, Mary (Oncology)
- 2Hugh, Judith (Laboratory Medicine and Pathology)
- 2McNeely, Margaret (Rehabilitation Medicine)
-
Giving Voice to the Unheard: Perceptions, Practices & Beliefs About Breast Cancer and Screening Among Ethnic Minority Women From the MENA (Middle East & North Africa) Region in Edmonton, Alberta.
DownloadFall 2019
Breast cancer is one of the major causes of death among women in Canada and globally. In Canada, screening has been found to be successful in decreasing morbidity and mortality (Canadian Cancer Society, 2015). Use of breast cancer screening services by immigrant women however is limited...
-
Regulation of Anti-tumor Immunity in Colorectal Cancer by Interaction of Exosome Immune Complexes with Fc gamma Receptors
DownloadSpring 2019
Targeted therapy is difficult for colorectal cancer (CRC) due to lack of conserved tumor associated antigens (TAA). Immunotherapies for CRC directed at TAA that can overcome intestinal tolerance need to be developed to improve survival of CRC patients. Exosomes are extracellular vesicles secreted...
-
Restoring Body Image after Breast Cancer through Exercise and Art Sculpture “RISE UP” after Breast Cancer: A Pilot Multi-Methods Study
DownloadFall 2020
The purpose of this thesis was to explore and describe body image in survivors of breast cancer in the context of supportive care, with specific focus on resistance exercise training and art therapy. The overall purpose of this work was to inform current practice and offer an alternative approach...
-
A Multi-perspective Concept Mapping Study of Head and Neck Cancer Treatment Outcome Priorities
DownloadFall 2020
Background Head and neck cancer treatments have been showing promising outcomes, yet they often have significant impact on patients. With an approximate 50% survival rate, individuals with a history of this type of cancer are living with long term challenges. With the increasing focus on...
-
A Novel Comparative Analysis Approach to Personalize Chemotherapy Dose Calculation in Early Breast Cancer
DownloadFall 2018
Background Worldwide, body surface area [BSA] is used to calculate chemotherapy dose. The BSA formula was originally developed in 1916, derived from height and weight, with no consideration of other patient characteristics. Most chemotherapy agents have a narrow therapeutic index and are...
-
Spring 2013
Polycomb protein methyltransferase, Enhancer of Zeste 2 (Ezh2), is frequently overexpressed in human malignancy and is implicated in cancer cell proliferation and invasion. Recently, several other polycomb proteins have been implicated in modulating the response to DNA double strand breaks, and...
-
Fall 2015
DNA is a detailed layout of instructions for cellular function. The integrity of human DNA is constantly challenged by a barrage of exogenous and endogenous sources. A regime of genome stability maintenance has evolved to repair the many different types of DNA damage. A form of communication...
-
Adiposity and fat loss in cancer: Exploring the prognostic significance and underlying mechanisms of adipose alterations in cancer
DownloadSpring 2017
During cancer progression, many patients will experience some degree of wasting of both muscle and adipose tissue. However, little is-known about adipose tissue alterations after a cancer diagnosis. Therefore, this research was conducted to first understand the prognostic significance of adipose...
-
Fall 2016
Antemortem identification of Creutzfeldt-Jakob disease (CJD) patients is initially based upon clinical presentation of the disease. Symptoms are assessed in combination with results from cerebrospinal fluid (CSF) analysis, electroencephalography (EEG), magnetic resonance imaging (MRI), and...
-
Anti-Cancer Mechanism of Trastuzumab via Blocking Nuclear HER2 Function and Epigenetic Mechanism of Resistance
DownloadSpring 2020
HER2 receptor tyrosine kinase (encoded by ERBB2 gene) is overexpressed in approximately 25% of all breast cancer tumors (known as HER2-positive breast cancers). Overexpression of HER2 causes overactivation of downstream receptor tyrosine kinase pathways including PI3K/Akt and MAPK pathways and is...