Search

Fall 2015

Murphy, Jeffrey Nathaniel

2015 marks the 50th anniversary of Moore's law, which has described the exponential progress in semiconductor patterning technologies, enabling creation of smaller circuitry features at greater densities. These continued hardware developments, economically mass manufactured, have made possible...

Fall 2016

Gushue, Danielle L

Antemortem identification of Creutzfeldt-Jakob disease (CJD) patients is initially based upon clinical presentation of the disease. Symptoms are assessed in combination with results from cerebrospinal fluid (CSF) analysis, electroencephalography (EEG), magnetic resonance imaging (MRI), and...

Fall 2012

Craik, Alison C

Taxane chemotherapy is widely used in the treatment of breast cancer. Despite its widespread clinical use, the molecular mechanisms of paclitaxel induced apoptosis remain unclear. Our laboratory has identified an important role for the BH3-only protein, BAD, in the paclitaxel induced cell death...

Fall 2017

Jin,Cong

The development of photolithography has been the main driving force of the semiconductor industry to keep pace with Moore’s Law for over five decades. The theoretical resolution limit of state-of-the-art 193 nm photolithography is about 36 nm (half pitch). By integrating multiple patterning...

2011-11-30

Murphy, Jeffrey N.

In order to adapt images of patterns templated using block copolymers, acquired using a scanning electron microscope, for publication, an algorithm was developed to process the images, enhancing the darker features in a consistent and easily reproducible manner. This was done using ImageJ, a free...

Fall 2015

Razavilar, Negin

In recent years, the application of self-associating block copolymer based drug delivery systems has attracted increasing attention as nano-sized carriers for the encapsulation and the controlled delivery of water insoluble drugs. Most of the drug formulations are based on the “trial and error”...

Spring 2010

Patel, Sarthakkumar

In recent years, the use of self-associating block copolymer based drug delivery systems have attracted increasing attention as nanoscopic carriers for the encapsulation and the controlled delivery of water insoluble drugs. Currently, most of the drug formulations proceed by “trial and error”...

Fall 2011

Binkhathlan, Ziyad

One of the major causes of failure in cancer chemotherapy is multidrug resistance (MDR), where cancer cells become resistant to different types of anticancer drugs. Over-expression of membrane efflux pumps like P-glycoprotein (P-gp), which recognizes different chemotherapeutic agents and...

Spring 2010

Mizuno, Hidenori

Nanoscale patterning of organic molecules has received considerable attention in current nanoscience for a broad range of technological applications. In order to provide a viable approach, this thesis describes catalytic stamp lithography, a novel soft-lithographic process that can easily...

Fall 2019

Brandwein, Daniel

14-3-3 proteins are a group of widely expressed, highly conserved homo/heterodimeric acidic proteins. They usually bind to serine/threonine phosphorylated proteins, but also bind to proteins in a phosphorylation-independent manner. 14-3-3 proteins have over 200 binding partners. 14-3-3 proteins...