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Skip to Search Results- 2Kinnaird, Adam
- 1Abdulsalam Alharbi
- 1Aktary, Zackie M
- 1Alolayan, Waad Riyad
- 1Alshamsan, Aws
- 1Amritpal Singh Bhullar
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Application of ROC curve analysis to metabolomics data sets for the detection of cancer in a mouse model
DownloadFall 2010
The goal of this study was to show that quantifiable metabolic changes may be used to screen for cancer. NIH III nude mice (n=22) were injected with human GBM cells, with daily urine samples collected pre and post-injection. 14 mice were injected with saline to serve as controls. The...
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Attitudes and Opinions of Pediatric Physicians Regarding Decisions to Withdraw or Withhold Medically-Provided Hydration or Nutrition
DownloadFall 2013
Deciding to forego intravenous hydration (IH) and medically-provided nutrition (MPN) in pediatric patients remains controversial. Minimal published research exists that explores the attitudes and approaches of pediatricians who are making these decisions. This survey explored attitudes and...
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B cell Tolerance Mechanisms Following ABO-incompatible Infant Heart Transplant: A Potential Role for CD22
DownloadSpring 2015
Due to presumed immune immaturity, infants are able to accept heart transplants across the ABO barrier, a procedure that would result in catastrophic consequences if performed in adults. Our group has demonstrated that following ABO-incompatible heart transplantation (ABOi HTx), infants develop...
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Fall 2012
Taxane chemotherapy is widely used in the treatment of breast cancer. Despite its widespread clinical use, the molecular mechanisms of paclitaxel induced apoptosis remain unclear. Our laboratory has identified an important role for the BH3-only protein, BAD, in the paclitaxel induced cell death...
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Fall 2018
Background: Cancer-associated venous thromboembolism (VTE) is associated with significant morbidity and mortality. Cancer patients are at higher risk of VTE recurrence despite anticoagulation and bleeding complications while on anticoagulation. There are some risk factors of bleeding specific...
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Fall 2020
Around the world, cancer is a leading cause of death and the burden of cancer is expected to increase in low-and middle-income countries (LMICs), where 82% of the world’s population resides. In these countries, which include Pakistan, aspects of the culture and traditions, inaccessibility to...
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Fall 2011
ABSTRACT Wnt signalling is of great biological importance as it has been implicated in development and cancer. The Wnt canonical pathway (WCP) is the best characterized signalling pathway. Based on my preliminary studies in my first and second years I found that the WCP is not linear and that it...
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Cognitive Dysfunction in non-Hodgkin's Lymphoma Patients Treated with Front-Line Chemotherapy
DownloadSpring 2015
Despite the research to date, the characteristics and impact of cognitive dysfunction (CD) in cancer patients following chemotherapy is still not well understood. It is estimated approximately 20% of patients will manifest measurable cognitive deficits on neuropsychological testing...
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Fall 2015
There is a concern that brain tumours are underreported in the Alberta Cancer Registry (ACR), yet no studies have been performed to investigate this issue. This study addresses the concern of underreporting of brain tumours in the ACR by assessing case ascertainment of primary brain tumours cases...
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Comparison of tooth loss between intensity modulated and non-intensity modulated radiotherapy in head and neck cancer patients
DownloadFall 2011
Advanced radiotherapy (RT) systems (intensity modulated radiotherapy, IMRT) is widely used to treat head and neck cancer. A combination of radiation and chemotherapy potentially increases toxicity as well as dental complications. Tooth loss was retrospectively assessed using oral cavity,...