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Skip to Search Results- 3Fliegel, Larry
- 3Moor, Andrea N.
- 1Durum, Scott K.
- 1Ferris, Douglas K.
- 1Fisher, Robert J.
- 1Gan, Xiaohong Tracey
- 1Cardiac Myocytes
- 1Cell Growth And Development
- 1Cultured-Cells
- 1Cytokine Receptors
- 1Flow-Cytometry
- 1Growth-Factors
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Activation of Na+/H+ exchanger-directed protein kinases in the ischemic and ischemic-reperfused rat myocardium
Download2001-01-01
Moor, Andrea N., Gan, Xiaohong Tracey, Karmazyn, Morris, Fliegel, Larry
The activity of the Na+/H+ exchanger has been implicated as an important contributing factor in damage to the myocardium that occurs during ischemia and reperfusion. We examined regulation of the protein in ischemic and reperfused isolated hearts and isolated ventricular myocytes. In isolated...
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Trophic factor withdrawal: p38 mitogen-activated protein kinase activates NHE1, which induces intracellular alkalinization
Download2001-01-01
Khaled, Annette R., Moor, Andrea N., Li, Aiqun Q., Kim, Kyungjae, Ferris, Douglas K., Muegge, Kathrin, Fisher, Robert J., Fliegel, Larry, Durum, Scott K.
Trophic factor withdrawal induces cell death by mechanisms that are incompletely understood. Previously we reported that withdrawal of interleukin-7 (IL-7) or IL-3 produced a rapid intracellular alkalinization, disrupting mitochondrial metabolism and activating the death protein Bax. We now...