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2013-02-04

Hamm, Michele, Vandermeer, Ben, Thomson, Denise, Milne, Andrea, Tjosvold, Lisa, Klassen, Terry P., Curtis, Sarah, Hartling, Lisa

BACKGROUND: Randomized controlled trials (RCTs) are the gold standard for trials assessing the effects of therapeutic interventions; therefore it is important to understand how they are conducted. Our objectives were to provide an overview of a representative sample of pediatric RCTs published in...

2013-02-04

Hartling, Lisa, Chisholm, Annabritt, Moher, David, Bow, Simon, Klassen, Terry P., Thomson, Denise, Tjosvold, Lisa, Klassen, Jeffrey

Background: Systematic reviews (SRs) are considered an important tool for decision-making. There has been no recent comprehensive identification or description of child-relevant SRs. A description of existing child-relevant SRs would help to identify the extent of available child-relevant...

2015

Milne, Andrea, Hartling, Lisa, Vandermeer, Ben, Freedman, Stephen B.

OBJECTIVE: To determine the most accurate, noninvasive method of assessing dehydration. STUDY DESIGN: The following data sources were searched: electronic databases, gray literature, scientific meetings, reference lists, and authors of unpublished studies. Eligible studies were comparative...

2013-02-15

Klassen, Terry P., Plint, Amy C., Vandermeer, Ben, Tjosvold, Lisa, Hartling, Lisa, Fernandes, Ricardo M., Patel, Hema, Bialy, Liza M., Johnson, David W.

Background: Bronchodilators are commonly used for acute bronchiolitis, despite uncertain effectiveness. Objectives: To examine the efficacy and safety of epinephrine in children less than two with acute viral bronchiolitis. Search methods: We searched CENTRAL (2010, Issue 3) which contains the...

2014-10-28

Campbell, Sandy, Dorgan, Marlene, Tjosvold, Lisa, Desmeules, Robin

2015/18/12

Castro Codesal, Maria L.

Introduction: Non-invasive ventilation (NIV) in children has become an increasingly common modality of breathing support where pressure support is delivered through a mask interface or less commonly through other non-invasive interfaces. At this time, NIV is considered a first-line option for...

2013-02-15

Joffe, Ari, Vandermeer, Ben, Hartling, Lisa, Lequier, Laurance, Larsen, Bodil, Anton, Natalie, Tjosvold, Lisa

Background: Nutritional support in the critically ill child has not been well investigated and is a controversial topic within paediatric intensive care. There are no clear guidelines as to the best form or timing of nutrition in critically ill infants and children. Objectives: To assess the...

2016-09-22

Adams, Denise, Terwee, Caroline B., Hansraj, Namrata, Hartling, Lisa, Vohra, Sunita, Bhaloo, Zafira, Liu, Yali

Objective: Conduct a systematic review of pediatric randomized controlled trials published in high impact journals to assess the reporting of primary outcomes and the psychometric properties of their measures. Study Design and Setting: Systematic review with screening and simultaneous data...