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Fall 2018

Clayton James Bell

Colchicine is an anti-mitotic drug that targets unpolymerized tubulin, and inhibits microtubule polymerization. It is primarily used to treat gout but has been investigated in numerous clinical trials to treat conditions such as leukemia (ALL), prostate cancer, and inflammatory diseases. However,...

Spring 2019

McLean, Cara

Abstract Background Medical interventions during childbirth are increasing, with cesarean section (CS) delivery exceeding recommended rates by 13-15 % in Canada. CS has been associated with gut dysbiosis in early life. Infants who bypass this beneficial maternal bacterial inoculation during...

Fall 2019

Motamedi, Melika

NK cells play an integral role in mediating immune responses to viral infections; however, their function is compromised during chronic diseases such as HIV-1, partly due to an increase in expression of inhibitory receptors. Thus, one of the reasons for the reduced immune responses elicited by NK...

Spring 2020

Alonge, Funmi

This study examines the negative impacts of climate change on the rights to life and health of marginalized communities by using as cases studies, rural Niger-Delta and Indigenous communities in oil producing areas of Nigeria and Canada. The case studies reveal that marginalization and inequality...

Spring 2019

Hillabrand, Rachel

Observations of tree dieback and mortality from climate change-induced drought has been documented across the world, however the mechanisms of tree mortality are not fully understood. Infestations of insect pests may also contribute to the process of drought-induced dieback. Tree physiological...

Fall 2018

Knaggs, Michelle

Wildfire shapes the boreal ecosystem in western Canada and thereby enhances and diminishes important breeding habitat for many songbird species. Two aspects of wildfire, burn severity and time since fire, fundamentally alter the forest structure that songbirds use. The objectives of this study...

Fall 2020

Zhang, Wu

Smart windows, having electrically-controlled transmission and zero-energy consumption when maintaining a colored or colorless state, increase the energy efficiency of buildings because they offer the potential to greatly reduce the energy cost of lighting, heating and cooling. Currently, the...

Fall 2018

Huang, Jian

In this study, the influence of dual bubble generator on mineral flotation was investigated. A Venturi-based dual bubble generator was designed and characterized in both liquid-gas two-phase system and solid-liquid-gas three-phase flotation system. The dual bubble generator featured immediately...

Spring 2020

Akude, Philip J

This thesis explores the impact of Ghana’s farm-gate cocoa price shocks on welfare. It comprises of two essays. The first essay examines the impact of a farm-gate cocoa price boom on child health, where the price boom directly affects household incomes and indirectly affect the investments in...

Spring 2020

Hulbah, Maram

Group B Streptococci (GBS) is the leading cause of invasive diseases in neonates, pregnant women and non-pregnant adult. In order to cause invasive disease, GBS encodes several virulence factors that are involved in the disease process. One such factor is the moonlighting glycolytic enzyme,...