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Skip to Search Results- 1Adam, Ibrahim S. Y.
- 1Airo, Adriana M
- 1Arendt, Christopher William.
- 1Awadh, Abdullah
- 1Azaizeh, Bara'ah
- 1Bacik, John-Paul
- 8Evans, David (Medical Microbiology and Immunology)
- 6Foley, Edan (Medical Microbiology and Immunology)
- 5Barry, Michele (Medical Microbiology and Immunology)
- 5Ingham, Robert (Medical Microbiology and Immunology)
- 5Ostergaard, Hanne (Medical Microbiology and Immunology)
- 4Baldwin, Troy (Medical Microbiology and Immunology)
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A large deletion virus reveals the presence of previously uncharacterized vaccinia virus inhibitors of NF-kB signaling
DownloadFall 2010
The classical Nuclear Factor kappa B (NF-κB) signaling pathway is an important regulator of inflammation and innate immune responses. Poxviruses, including vaccinia virus, encode multiple immune evasion proteins, including a growing number of NF-κB inhibitors. To determine if additional vaccinia...
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A tale of two hypotheses: Effect of the herpes simplex-1 virus virion host shutoff (vhs) protein on bicistronic reporters
DownloadFall 2014
The herpes simplex virus virion host shutoff (vhs) protein acts as an mRNA specific endoribonuclease. Our lab has previously determined that vhs stimulates expression of the 3’ CAT cistron of a bicistronic reporter plasmid while under the influence of the BiP IRES; however, the mechanism by which...
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Fall 2020
Introduction: ABO-incompatible organ transplants (ABOi-Tx) recipients are at high-risk of rapid rejection mediated by ABO antibodies (ABO Abs). To manage and expand ABOi-Tx, it is necessary to understand the mechanism(s) by which natural and induced ABO Abs develop. Prior studies have used...
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Spring 2022
Positive strand RNA ((+)ssRNA) viruses are some of the most important pathogens that impact the public health, economy, and quality of life. The interferon (IFN) response plays a critical role in innate immune response targeting (+)ssRNA viruses, which in turn have evolved various strategies to...