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Skip to Search Results- 33Mass-spectrometry
- 29Chemistry
- 23Organic compounds. Synthesis.
- 22Catalysis
- 22Metabolomics
- 21Capillary electrophoresis.
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Fall 2024
Mesoporous silica nanoparticles (MSNPs) are used in catalysis, drug delivery, controlled drug release, imaging and biosensing applications due to their stability, high pore volumes, large surface area and non-toxicity. Although MSNPs have many advantages in biological applications, they lack...
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Synthesis of Hyper-branched Oligosaccharide Epitopes from Glycoprotein GP72 of T. cruzi and Evaluation of their Binding to the WIC26.29 Monoclonal Antibody
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Chagas disease is caused by the parasitic protozoan Trypanosoma cruzi, which is transmitted to humans mostly by contact with insects called ‘kissing bugs’. The presence of an immunogenic glycoprotein, GP72, on the cell surface of T. cruzi has a key role in the parasite’s life cycle. A monoclonal...
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Advancing Lipidomics through Method Development, Data Processing, and its Applications in Cancer Research
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Lipidomics, a subfield of metabolomics, offers comprehensive insights into the lipid composition of biological systems. Lipids, comprising a broad class of biological molecules, are essential to several biological functions. They play critical roles in cell membrane formation, serving as...
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Fall 2024
Sialylation is a crucial post-translational modification that covalently attaches sialic acid to glycoproteins and glycolipids, and is driven by a superfamily of enzymes called sialyltransferases (STs). Alterations in sialylation have been identified in different biological contexts including...
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Chemical Characterization of Indoor Air Pollutants: Implications to Consumer and Occupational Health
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Humans living in the contemporary societies find the majority of their time spent indoors, promoting awareness regarding indoor air quality over the past decades. The indoor environment has gained significant complicity due to an increasing variety of inhalable products consumed in our daily...
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Synthesis of High-Entropy Alloy Nanoparticles and Compounds Using Germanium-Based Nanostructures
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High-entropy alloy nanoparticles and compounds exhibit significant potential in various emerging energy storage and conversion fields due to their compositional flexibility for precise tuning of desired functionalities. The research described in this thesis aims to explore germanium-based...
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Fall 2024
Despite the widespread use of hydrofluoric acid (HF) in the preparation of silicon surfaces, the true nature of fluorinated surface species remains unclear. Here, an array of characterization techniques led by solid-state nuclear magnetic resonance spectroscopy is employed to uncover the nature...
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Development and Application of Advanced Mass Spectrometry Techniques for Determination of Reactive Aerosol Constituents
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Reactive aerosol constituents, including organic peroxides (H2O2, ROOR and ROOH), organosulfates (OS), and organonitrates (ON), are integral components of atmospheric chemistry, climate dynamics, and human health. However, their intricate chemical compositions and dynamic behaviours present...