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Skip to Search Results- 1Abbasi Dezfouli, Meysam
- 1Akin, Oguz
- 1Amin, Muhammad Ruhul
- 1Arkell, Nicholas P
- 1Bayati, Fatemeh
- 1Bell, Wayne Ronald Victor
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Delivery of STAT3 inhibitor cucurbitacins to tumor by polymeric nano-carriers : Implications in cancer chemo- and immunotherapy
DownloadFall 2009
Signal Transducer and Activator of Transcription 3 (STAT3), a common oncogenic mediator, is constitutively activated in many types of human cancers and plays a critical role in tumor growth and cancer immune evasion. The focus of this dissertation is the delivery of STAT3 inhibitor cucurbitacins...
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Lipid Modified Polymers for Transfection of Human CRL Fibroblasts, and for siRNA Mediated MDR Reversal in Melanoma Cancer Therapy
DownloadFall 2010
Gene delivery for therapeutic purposes is quickly emerging as the best potential treatment option for inherited genetic diseases and cancer. Viral gene carriers have been the choice for this purpose due to their high efficiency, but harmful immunogenic and oncogenic host reactions have limited...
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Regional and local controls of surface water chemistry in the Boreal Plain and Shield transition of Canada
DownloadFall 2010
The Western Boreal Forest exhibits complex hydrogeology juxtaposed with rapid resource development. Predicting surface water chemistry to assess the influence of landuse and climate change is needed. The research purpose was to test if a global model (Gibbs), used to assess water chemistry...
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Synthesis and Characterization of Phosphorylcholine-based Polymers and Nanogels via the Reversible Addition Fragmentation Chain Transfer Process
DownloadFall 2011
2-Methacryloyloxyethyl Phosphorylcholine is an interesting biocompatible monomer. An improved method for the synthesis of poly(MPC) and its copolymers using Reversible Addition-Fragmentation chain Transfer (RAFT) has been discussed in the first part of the thesis. Previous reports related to the...
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Fall 2011
Coupling supercritical CO2 extraction with membrane separation leads to energy savings by recycling CO2 at supercritical state while separating extract components. Commercially available polyamide-based membranes are commonly used with coupled systems due to their availability and robust...
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Spring 2012
Germanium nanomaterials have many potential applications based on their size-tunable optical and electronic properties, for example in photodetectors, photovoltaics and non-volatile memory. In this work, the synthesis of Ge nanoparticles by two different methods based on tailorability through the...
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Spring 2012
The study of heterobimetallic complexes (having two different metal atoms) involves combining the unique properties of each metal, which can give rise to interesting contrasts in reactivity compared to either metal alone. With two different metals incorporated into one complex, a more diverse...
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Fall 2012
Processing of oil sands ores to extract bitumen generates large volumes of tailings which are deposited into large settling basins, where the solids settle by gravity over 3-4 years to become mature fine tailings (MFT). Methanogenesis has been correlated with increased water recovery from and...
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Synthetic Main Group and Transition Metal Targets for Electronic and Photovoltaic Applications
DownloadFall 2012
The work presented herein is focused on the synthesis and characterization of inorganic materials for potential use in electronic and photovoltaic applications. Platinum containing complexes of the form LxPt(SC4H2Br)2 (x = 1, L = dppe, dppp; x = 2, L = PBu3, PAr3), were synthesized using...