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The research presented in this work explores the application of microfluidics to the field of proteomics through the design of a multi-channel microfluidic platform and the investigation of individual components of the system. The design of this microfluidic device allows the integration of...
Cellulose nanocrystals (CNCs) are an emerging renewable and sustainable nanomaterial which has received increasing attention. They are abundant, nontoxic, biodegradable and chemically inert. CNCs have unique characteristics not met by traditional cellulose-derived materials, leading...
The development of rapid and bioorthogonal chemical reactions has expanded greatly the utility of bioconjugation chemistry in the service of site-selective protein labeling, even allowing molecular imaging in live cells or animals. âClickâ chemistry is particularly desirable due to its fast...
Interfacing Silicon-Based Quantum Dots with Proteins for Biological and Sensing ApplicationsDownload
This dissertation presents the preparation of functional bioinorganic hybrids from silicon-based quantum dots (SiQDs) and enzymes and the use of SiQDs and green fluorescent protein as ratiometric photoluminescent sensors for nerve agents. Chapter 2 discusses the preparation of water-soluble...