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Spring 2010
The research presented in this work explores the application of microfluidics to the field of proteomics through the design of a multi-channel microfluidic platform and the investigation of individual components of the system. The design of this microfluidic device allows the integration of...
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Spring 2018
The development of rapid and bioorthogonal chemical reactions has expanded greatly the utility of bioconjugation chemistry in the service of site-selective protein labeling, even allowing molecular imaging in live cells or animals. âClickâ chemistry is particularly desirable due to its fast...
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Interfacing Silicon-Based Quantum Dots with Proteins for Biological and Sensing Applications
DownloadFall 2020
This dissertation presents the preparation of functional bioinorganic hybrids from silicon-based quantum dots (SiQDs) and enzymes and the use of SiQDs and green fluorescent protein as ratiometric photoluminescent sensors for nerve agents. Chapter 2 discusses the preparation of water-soluble...