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Skip to Search Results- 3Field, Catherine J.
- 1Adam, Ibrahim S. Y.
- 1Baracos, Vickie E.
- 1Casey, Geoffrey A
- 1Clandinin, M. Thomas
- 1Coltman, D. W.
- 13Graduate and Postdoctoral Studies (GPS), Faculty of
- 13Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 4Agricultural, Food and Nutritional Science, Department of
- 4Agricultural, Food and Nutritional Science, Department of/Journal Articles (Agricultural, Food and Nutritional Science)
- 1Biological Sciences, Department of
- 1Biological Sciences, Department of/Journal Articles (Biological Sciences)
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Glutamine supplementation improves intestinal barrier function in a weaned piglet model of Escherichia coli infection
Download2011
Johnson, Ian R., Ewaschuk, Julia B., Murdoch, Gordon K., Field, Catherine J., Madsen, Karen L.
The weaning period is associated with an increased prevalence of gastrointestinal infection in many species. Glutamine (Gln) has been shown to improve intestinal barrier function and immune function in both in vivo and in vitro models. The objective of the present study was to determine the...
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2018-10-16
SSHRC NFRF-E awarded 2019: With the requested funding, I will apply my expertise in T cells and metabolism to identify new potential metabolic drugs that can enhance immune function. We hypothesize that a Insulin-Resistance (IR)-related immune and metabolic defect contributes to increased risk of...
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Spring 2024
To maintain an effective barrier, intestinal epithelial progenitor cells must divide at a rate that matches the loss of dead and dying cells. Epithelial damage during most enteric infection accelerates cell proliferation and tissue repair via multiple stress responses. However, infection with the...
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Innate Immunity and the Retinal Pigment Epithelium in Gene Therapy for Inherited Retinal Disorders
DownloadFall 2021
Background: The photoreceptors are post-mitotic (no longer dividing), so the eye has evolved several unique immunological mechanisms to protect the photoreceptors and prevent vision loss. Inherited retinal disorders occur when mutations disrupt normal retinal function and photoreceptors die....
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Prophylactic ciprofloxacin treatment prevented high mortality, and modified systemic and intestinal immune function in tumour-bearing rats receiving dose-intensive CPT-11 chemotherapy
Download2009
Baracos, Vickie E., Xue, Hongyu, Sawyer, Michael B., Field, Catherine J
Infectious complications are a major cause of morbidity and mortality from dose-intensive cancer chemotherapy. In spite of the importance of intestinal bacteria translocation in these infections, information about the effect of high-dose chemotherapy on gut mucosal immunity is minimal. We studied...
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Spring 2023
Glycosylation is the enzymatic modification of biomacromolecules (proteins, etc.) with carbohydrates known as glycans. Naturally occurring in all organisms from viruses to animals, glycans have multifaceted functions in all aspects of biology. Aberrant glycosylation is often observed in diseases...
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The Role of Haemocytes in the Immune Response of Biomphalaria glabrata against Schistosoma mansoni: Investigations into Haematopoiesis and Pattern Recognition Receptors
DownloadSpring 2018
Snails (Gastropoda) serve as hosts for the larval development of many medically and agriculturally important digenean trematodes (parasitic flatworms), including schistosomes, blood flukes that collectively infect more than 260 million people globally. Compatibility between snails and digeneans...
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Fall 2017
The inflammatory response is a complex biological process initiated following the recognition of noxious stimuli. It is composed of an elaborate cascade of both pro- and anti-inflammatory mediators, essential for effective defenses against infection, the removal of damaged cells, and the...
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Toxic effects induced in mammalian immune cells after in vitro exposure to oil sands process-affected water and its fractions
DownloadFall 2019
Oil sands process-affected water (OSPW) is produced by the surface mining industry in Alberta as a byproduct of the Clark hot water process, the currently used extraction method of crude oil from bitumen/tar sands. Under a provincial zero release policy all produced OSPW must be stored on site....