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Skip to Search Results- 1Githaka, John M
- 1Harbison, Adrian Mark.
- 1Howlader, Md Amran
- 1Ling, Jennifer YM
- 1Locke, Andrew J
- 1Owttrim, George W.
- 7Graduate and Postdoctoral Studies (GPS), Faculty of
- 7Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 1Biological Sciences, Department of
- 1Biological Sciences, Department of/Other Publications (Biological Sciences)
- 1ERA General Collection
- 1ERA General Collection/Supplementary Thesis Materials (ERA General)
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Fall 2014
Fungal pathogens are recognized by Dectin-1, a pattern recognition receptor expressed on mammalian innate immune cells. Dectin-1 detects β-glucans, which are polymers of glucose that are a main component of the fungal cell wall. While purified, soluble β-glucans have been used in the clinic as...
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Coming in from the cold: spatiotemporal regulation of gene expression by the cyanobacterial RNA helicase redox (CrhR) during abiotic stress - Supplementary Data
Coming in from the cold: spatiotemporal regulation of gene expression by the cyanobacterial RNA helicase redox (CrhR) during abiotic stress - Supplementary Data
Download2024-05-10
Contains supplementary protein quantification files and cell imaging movies related to the thesis Coming in from the cold: spatiotemporal regulation of gene expression by the cyanobacterial RNA helicase redox (CrhR) during abiotic stress, Brendan T. Whitman, Spring 2024
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Fall 2020
RNA helicases function in all aspects of RNA metabolism, regulating a diverse range of cellular processes by rearranging RNA structures and mediating RNA-protein interactions. Prokaryotic RNA helicases have been shown to have roles in RNA degradation, ribosome biogenesis and translation, with...
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Fall 2013
West Nile virus (WNV) is a neurotropic, blood-borne flavivirus that can cause serious neurological disease in humans and animals. While significant progress has been made in identifying virus-encoded pathogenic determinants, very little is known regarding how these viral proteins interact with...
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Spring 2020
The human neuraminidases (NEU1, NEU2, NEU3, and NEU4) are a family of enzymes implicated in pathologies including cancer and diabetes. Our group has developed selective inhibitors for these enzymes that have been employed as tools to understand their biological roles. Several reports have linked...
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2012-06-21
Whitford, Denise S., Owttrim, George W.
Expression of the stress-regulated RNA helicase of Synechocystis sp. PCC 6803, CrhR, is altered by three known stresses, temperature, light and salt concentration. Here we show that altering the source of fixed nitrogen, either urea, ammonia, nitrate or lack of fixed nitrogen, also results in...
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Plasma Membrane Organization and Endocytosis of CD36 in Human Microvascular Endothelial Cells
DownloadSpring 2016
The plasma membrane is a dynamic lipid bilayer that surrounds the cell, embedded with different plasma membrane proteins, aiding communication between the inside and outside of the cells. Its functions are achieved through an intricate organization of lipid-lipid, lipid-protein and...
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Fall 2017
Protein prenylation is the post-translational addition of isoprenoid lipid moieties to proteins, which regulates their subcellular localization and function. Farnesyl or geranylgeranyl isoprenoids are covalently linked to cysteines residues in a C-terminal prenylation recognition sequence in...