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Skip to Search Results- 2Elahi, Shokrollah
- 2Field, Catherine J.
- 2Goruk, Susan
- 2Koleva, Petya
- 2Richard, Caroline
- 1Akinwumi, Segun M
- 21Graduate and Postdoctoral Studies (GPS), Faculty of
- 21Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 2Agricultural, Food and Nutritional Science, Department of
- 2Agricultural, Food and Nutritional Science, Department of/Journal Articles (Agricultural, Food and Nutritional Science)
- 2WISEST Summer Research Program
- 2WISEST Summer Research Program/WISEST Research Posters
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Characterization of Binding of LILRA3 and LILRB2 to the Myelin-Associated Inhibitors and Major Histocompatibility Class I Molecules
DownloadFall 2018
The leukocyte immunoglobulin-like receptor family (LILR) is composed of inhibitory and activating receptors that are widely expressed on immune cells and interact with classical and non-classical MHC-I. Recently, several ligands have been identified for the LILRs including the three...
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2015
Field, Catherine J., Lewis, Erin, Curtis, Jonathan M., Richard, Caroline, Goruk, Susan, Jacobs, Rene L., Ruth, Megan R., Dellschaft, Neele S.
Choline demands during lactation are high; however, detailed knowledge is lacking regarding the optimal dietary intake during this critical period. The present study was designed to determine the effects of varying intakes of choline on maternal immune function during lactation. Primiparous...
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Spring 2013
The adaptive immune response against intracellular pathogens is largely mediated by CD8+ T lymphocytes. The clonal expansion and expression of cytolytic and immune stimulatory proteins by CD8+ T cells is responsible for their protective immune function. Prior to exhibiting effector activity,...
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Creation of an in-vitro¬ Co-culture Model of Microglia and Retinal Pigment Epithelium Cells for Investigating the Innate Immune Mechanisms of the Retina
DownloadFall 2022
Background: The immune mechanisms of the retina in response to gene therapy have been previously understudied due to assumptions of ocular immune privilege. Ocular immune privilege is the concept that there is a tolerance or reduced immune response to antigen exposure in the eye. With the recent...
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Developing clinically translatable chimerism induction protocols in a stringent murine model
DownloadSpring 2020
Allogeneic hematopoietic chimerism induction via bone marrow transplantation (BMT) is thus far the most robust method for inducing donor antigen specific tolerance to allogeneic grafts. However, limited by the toxicity of the reagents used in conditioning the recipients, the demand of a high dose...
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Spring 2014
The development of rapid detection techniques to be applied at the point of use, has been gaining significant attention in the recent years. Rapid techniques are important and preferable methods in healthcare and environment sector due to the advantages they offer such as low-cost and reduced...
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E.coli and bacteriophage T4: Using lytic bacteriophages to prevent tissue culture contamination
Download2014-07-04
Bacteria are commonly encountered cell culture contaminants. Due to the costly consequences of media contamination and the loss of research production, further research should be devoted to the prevention of contamination so time and money are not wasted. Phage have been demonstrated to prevent...
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Fall 2022
Affinity maturation is the process to improve antibody affinity for an antigen during an adaptive immune response; it is mediated by the immunoglobulin mutator enzyme activation-induced cytidine deaminase (AID). This process is crucial to produce high-affinity memory B-cells and plasma cells. In...
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Examining the Effects of Cytoplasmic Tail Splicing Event in Goldfish (Carassius auratus) Leukocyte Immune-type receptors
DownloadSpring 2024
The innate immune system is important in clearing infections and maintaining homeostasis. Across vertebrates, innate immunity is capable of executing potent effector responses through the actions of highly specialized cells. Effector responses, such as phagocytosis and cytokine secretion, are...
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Feeding a diet enriched in docosahexaenoic acid to lactating dams improves the tolerance response to egg protein in suckled pups
Download2016
Field, Catherine J., Lewis, Erin D., Richard, Caroline, Goruk, Susan
The objective of this study was to determine the effect of feeding a maternal diet supplemented with docosahexaenoic acid (DHA) during the suckling period on the development of the immune system and oral tolerance (OT) in offspring. Dams were randomized to consume one of two nutritionally...