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Skip to Search Results- 2Finlay, Warren H.
- 2Löbenberg, Raimar
- 1Al-Hallak, M. H. D. Kamal
- 1Arshad, Muhammad
- 1Azarmi, Shirzad
- 1Bachynsky, J.
- 10Graduate and Postdoctoral Studies (GPS), Faculty of
- 10Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 3Pharmacy and Pharmaceutical Sciences, Faculty of
- 3Pharmacy and Pharmaceutical Sciences, Faculty of/Journal Articles (Pharmacy and Pharmaceutical Sciences)
- 1Chemistry, Department of
- 1Chemistry, Department of/Journal Articles (Chemistry)
- 1Dr. Afsaneh Lavasanifar (Faculty of Pharmacy and Pharmaceutical Sciences)
- 1Finlay, Warren (Mechanical Engineering)
- 1Lavasanifar, Afsaneh (Faculty of Pharmacy and Pharmaceutical Sciences)
- 1Le, Xiao-Chun Chris (Department of Laboratory Medicine and Pathology)
- 1Li, Xing-Fang (Laboratory Medicine and Pathology)
- 1Martin, Andrew
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Advancements in Metered-Dose Inhaler Technology: Feasibility of Excipients and Particle Size Prediction
DownloadSpring 2024
Chronic respiratory diseases such as chronic obstructive pulmonary disease (COPD) are one of the leading causes of death in the world. According to the World Health Organization (WHO), 262 million people were diagnosed with Asthma in 2019 alone. Among current drug delivery systems for the...
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Spring 2011
The objective of this thesis is to design nanoparticle (NP)-based drug delivery systems suitable for treatment of bone diseases. Two types of nanocarriers, (1) polymer coated bovine serum albumin (BSA) NPs and (2) lipid based NPs (micelles and liposomes) were investigated. The BSA NPs were...
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Cell-electronic Sensing of Cellular Responses and Toxicity Induced by Nanoparticles and Arsenic Species
DownloadFall 2013
We demonstrate the development of a real-time cell analysis (RTCA) platform for studying nanoparticle- and arsenic-induced cytotoxicity with potential applications to risk assessment, environmental toxicity monitoring, and drug development. RTCA is an impedance-based in vitro detection system...
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2015
Guo, Siyuan, Zhang, Qiang M., Serpe, Michael J., Wei, Menglian, Gao, Yongfeng
A device constructed by sandwiching a thin film of poly(N-isopropylacrylamide)-co-acrylic acid (pNIPAmco-AAc) microgels between two thin layers of Au (all on a glass support) was used as a novel platform for controlled release of small molecules (drugs). In this submission, the model drug tris...
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Experimental and theoretical studies on the particle formation process of particles for the improvement of pulmonary drug delivery
DownloadFall 2016
The formation of dry microparticles from evaporating solution droplets was investigated and analyzed. The particle formation involved the creation and production of spray dried microparticles used for the delivery of drugs to treat pulmonary diseases. Studies of particle formation were conducted...
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Fall 2021
In this thesis, several fundamental studies were conducted to tackle some of the unanswered questions in the design and engineering of inhalable microparticles produced via spray drying. Different experimental and theoretical methods were applied to understand the mechanisms that control particle...
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Nanodelivery of Novel Inhibitors of ERCC1/XPF for sensitizing colorectal cancer cell to platinum drugs
DownloadSpring 2023
This project's long-term goal is to increase the efficacy of genotoxic therapeutics through thesensitization of cells to DNA-damaging therapy ahead of the treatment. The focus of this projectwas on the enhancement of platinum-based chemotherapeutics in colorectal cancer usingcolorectal cancer...
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Spring 2012
The present thesis describes preliminary studies required for evaluating silicon nanocrystals (Si-NCs) as photothermal (PT) therapy agents and drug delivery vehicles. Group 14 semiconductor NCs are of particular interest for these applications because of their tailorable optical response and...