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Skip to Search Results- 8University of Alberta, Department of Biological Sciences
- 7Wang, J.
- 5Wishart, D.S.
- 4Brigandt, Ingo
- 4Rankin, Robert
- 4Wong, G.K.S.
- 72Graduate and Postdoctoral Studies (GPS), Faculty of
- 72Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 44Biological Sciences, Department of
- 36Biological Sciences, Department of/Journal Articles (Biological Sciences)
- 8Biological Sciences, Department of/BioSci OER
- 7Philosophy, Department of
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Carotenoid diversity in novel Hymenobacter strains isolated from Victoria Upper Glacier, Antarctica, and implications for the evolution of microbial carotenoid biosynthesis
DownloadFall 2009
Many diverse microbes have been detected in or isolated from glaciers, including novel taxa exhibiting previously unrecognized physiological properties with significant biotechnological potential. Of 29 unique phylotypes isolated from Victoria Upper Glacier, Antarctica (VUG), 12 were related to...
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Characterisation of novel potential phosphorylation sites in the tumour suppressor Merlin in Drosophila
DownloadFall 2014
Neurofibromatosis Type II is an inherited cancer that manifests as various tumours in the nervous system. Mutations and deletions in the tumour suppressor Merlin (moesin, ezrin, radixin-like protein) are linked to the development of the disease. The mechanism by which Merlin suppresses cell...
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Characterisation of the Non-Canonical Translation Initiation Factor eIF4E-3 as a Merlin Interacting Protein in Drosophila melanogaster
DownloadSpring 2016
Merlin is a tumour suppressor protein, the loss of which is linked to the inherited nervous system tumour syndrome Neurofibromatosis type 2 as well as sporadic tumour development. It is related to the ERM (ezrin-radixin-moesin) protein family, which is involved in linking the cytoskeleton to...
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2009
Grant, Jason, Stothard, Paul, Moore, Stephen S., Guan, Leluo, Jin, Weiwu
Background MicroRNAs (miRNAs) are a family of ~22 nucleotide small RNA molecules which regulate gene expression by fully or partially binding to their complementary sequences in mRNAs or promoters. A large number of miRNAs and their expression patterns have been reported in human, mouse and rat....
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Fall 2017
Merlin and the ezrin-radixin-moesin (ERM) proteins are key organizers of the cell cortex through linking membrane-associated proteins to the underlying actin cytoskeleton. Merlin and the ERM proteins have been implicated in the maintenance of cell integrity, adhesion, and motility during tissue...
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Characterization of the crosstalk between immunity and metabolism in Drosophila melanogaster model
DownloadFall 2021
Immune and metabolic pathways collectively contribute to the containment of microbial invaders, and persistent activation of immune responses contribute to the development of severe metabolic disorders. To determine how interaction between innate immune system and metabolic responses affected...
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Classifying Crystal Structures of Binary Compounds AB through Cluster Resolution Feature Selection and Support Vector Machine Analysis
Download2016
Adutwum, Lawrence A. , Harynuk, James, Mar, Arthur, Oliynyk, Anton O.
Partial least-squares discriminant analysis (PLS-DA) and support vector machine (SVM) techniques were applied to develop a crystal structure predictor for binary AB compounds. Models were trained and validated on the basis of the classification of 706 AB compounds adopting the seven most common...
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Comparative Analysis of the Anatomy of the Myxinoidea and the Ancestry of Early Vertebrate Lineages
DownloadFall 2012
The question of whether a hagfish is a true vertebrate or not has profound implications about the ancestry of the clade. New anatomical evidence allows a test of their systematic position. With dissections and serial sections of original specimens, and with a literature review, a comparative...
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Comparative analysis of two phenotypically-similar but genomically-distinct Burkholderia cenocepacia-specific bacteriophages
Download2012
Stothard, Paul, Dennis, Jonathan J., Lynch, Karlene H.
Background Genomic analysis of bacteriophages infecting the Burkholderia cepacia complex (BCC) is an important preliminary step in the development of a phage therapy protocol for these opportunistic pathogens. The objective of this study was to characterize KL1 (vBBceSKL1) and AH2 (vBBceSAH2),...