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Skip to Search Results- 1Githaka, John M
- 1Hagen, Mariel O
- 1Harbison, Adrian Mark.
- 1Howlader, Md Amran
- 1Joshi, Reema
- 1Katzenback, Barbara A
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Analysis of goldfish innate immunity following exposure to oil sands process affected water
DownloadFall 2013
The acute and sub chronic effects of oil sands process affected water (OSPW) and its toxic component, naphthenic acids (NAs) were examined. I exposed goldfish for one (acute), or 12 (sub chronic) weeks and examined immune gene expression, macrophage function, the ability of exposed fish to...
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Analysis of the acute phase response in goldfish (Carassius auratus L.) infected with Trypanosoma carassii
DownloadSpring 2016
The innate immune response is a fundamental defense mechanism in bony fishes and a crucial component of innate immunity is the acute phase response (APR). The APR is a systemic and/or local response to any injury, infection, or trauma and is characterized by a change in the blood composition of...
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Fall 2014
Fungal pathogens are recognized by Dectin-1, a pattern recognition receptor expressed on mammalian innate immune cells. Dectin-1 detects β-glucans, which are polymers of glucose that are a main component of the fungal cell wall. While purified, soluble β-glucans have been used in the clinic as...
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Spring 2024
Ancient philosophers observed and documented fever as an increased body temperature in response to infection. Nowadays, fever is regarded as a symptom of infection and inflammation and therefore is often supressed by NSAID drugs. A common hypothesis for the benefits of a fever is that the rise in...
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Fall 2013
West Nile virus (WNV) is a neurotropic, blood-borne flavivirus that can cause serious neurological disease in humans and animals. While significant progress has been made in identifying virus-encoded pathogenic determinants, very little is known regarding how these viral proteins interact with...
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Magazine Images Depicting the Ideal Fit Male Body: An Outlet for Influencing Body Perceptions and Exercise Related Cognitions
DownloadFall 2012
This study examined the effects of viewing health/fitness and sports magazine images on body perceptions and exercise related cognitions in males. The moderating effects of age were also examined. A series of 3 (image-only, magazine cover, control) by 3 (youngest, middle, oldest) ANOVA analyses...
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Spring 2020
The human neuraminidases (NEU1, NEU2, NEU3, and NEU4) are a family of enzymes implicated in pathologies including cancer and diabetes. Our group has developed selective inhibitors for these enzymes that have been employed as tools to understand their biological roles. Several reports have linked...
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Pathophysiology in fish trypanosomiasis: The interaction between Trypanosoma carassii and goldfish erythropoietic system during the course of infection
DownloadFall 2019
Trypanosoma carassii is a hemoflagellate parasite that infects a variety of cyprinid fish. The primary pathophysiology of T. carassii infections in fish is the onset of a prolonged anemia, characterized by significant decreases in the number of circulating red blood cells during peak parasitemia....