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- 16Biological Sciences, Department of/Journal Articles (Biological Sciences)
- 12Agricultural, Food and Nutritional Science, Department of
- 12Agricultural, Food and Nutritional Science, Department of/Journal Articles (Agricultural, Food and Nutritional Science)
- 7Roy Berg Kinsella Research Ranch
- 7Roy Berg Kinsella Research Ranch/Journal Articles (Kinsella Ranch)
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Gawky Is a Component of Cytoplasmic mRNA Processing Bodies Required for Early Drosophila Development
Download2006
Hobman, T. C., Locker, J., Schneider, M. D., Pare, J. M., Haskins, J., Simmonds, A. J., Chaker, S., Najand, N
In mammalian cells, the GW182 protein localizes to cytoplasmic bodies implicated in the regulation of messenger RNA ( mRNA) stability, translation, and the RNA interference pathway. Many of these functions have also been assigned to analogous yeast cytoplasmic mRNA processing bodies. We have...
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2004
Fu, A., Li, C., Moore, S. S., Dixon, W. T., Hansen, C., Christopherson, R.
Adipogenesis is of significant relevance from an agricultural perspective. Traits such as subcutaneous fat thickness, marbling and waste fat are of substantial economic importance in animal production. In order to discover more about the genetic basis of this process, a study was undertaken to...
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Generation, annotation, analysis and database integration of 16,500 white spruce EST clusters
Download2005
Johnson, J.E., Pavy, N., Cooke, J., Parsons, L., Paule, C., Morency, M.J., Crow, J.A.
Background: The sequencing and analysis of ESTs is for now the only practical approach for largescale gene discovery and annotation in conifers because their very large genomes are unlikely to be sequenced in the near future. Our objective was to produce extensive collections of ESTs and cDNA...
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Genome wide identification and functional prediction of long non-coding RNAs responsive to Sclerotinia sclerotiorum infection in Brassica napus
Download2016
Rahman, Muhammad H., Megha, Swati, Joshi, Raj K., Basu, Urmila, Kav, Nat N. V.
Sclerotinia stem rot caused by Sclerotinia sclerotiorum affects canola production worldwide. Emerging evidence suggests that long non-coding RNAs (lncRNAs) play important roles in the regulation of gene expression in plants, in response to both abiotic and biotic stress. So far, identification of...
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2007
Seligmann, B., Deyholos, M., Kris, R. M., Felder, S., Botros, I., Galbraith, D. W., Martel, R., Hinton, J., Lambert, G. M.
High-throughput gene expression analysis of genes expressed during salt stress was performed using a novel multiplexed quantitative nuclease protection assay that involves customized DNA microarrays printed within the individual wells of 96-well plates. The levels of expression of the transcripts...
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Homology in comparative, molecular, and evolutionary developmental biology: The radiation of a concept
Download2003
The present paper analyzes the use and understanding of the homology concept across different biological disciplines. It is argued that in its history, the homology concept underwent a sort of adaptive radiation. Once it migrated from comparative anatomy into new biological fields, the homology...
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IL-6 indirectly modulates the induction of glyceroneogenic enzmes in adipose tissue during exercise
Download2012
Wan, Zhongxiao, Beaudoin, Marie-Soleil, Castellani, Laura, Wright, David C., Ritchie, Ian, Chan, Catherine B.
Background Glyceroneogenesis is an important step in the control of fatty acid re-esterification with PEPCK and PDK4 being identified as key enzymes in this process. We have previously shown that glyceroneogenic enzymes such as PDK4 are rapidly induced in white adipose tissue during exercise....
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2012
Wan, Zhongxiao, MacDonald, Tara, Wright, David C., Holloway, Graham P., Chan, Catherine B., Perry, Christopher G.
Background Adipose tissue mitochondria have been implicated as key mediators of systemic metabolism. We have shown that IL-6 activates AMPK, a mediator of mitochondrial biogenesis, in adipose tissue; however, IL-6−/− mice fed a high fat diet have been reported to develop insulin resistance. These...
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Maternal and Paternal Genomes Differentially Affect Myofibre Characteristics and Muscle Weights of Bovine Fetuses at Midgestation
Download2013
Kruk, Z. A., Xiang R., Rutley, D. L., Thomsen, D. A., Anderson, G. I., Fitzsimmons, C., Ghanipoor-Samami, M., Hiendleder, S., Roberts, C. T., Eindorf, T., Burns, B. M., Greenwood, P. L., Johns, W. H.
Postnatal myofibre characteristics and muscle mass are largely determined during fetal development and may be significantly affected by epigenetic parent-of-origin effects. However, data on such effects in prenatal muscle development that could help understand unexplained variation in postnatal...
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MicroRNA Buffering and Altered Variance of Gene Expression in Response to Salmonella Infection
Download2014
Plastow, G. S., Bao, H., Kommadath, A., Guan, L. L., Tuggle, C. K., Stothard, P.
One potential role of miRNAs is to buffer variation in gene expression, although conflicting results have been reported. To investigate the buffering role of miRNAs in response to Salmonella infection in pigs, we sequenced miRNA and mRNA in whole blood from 15 pig samples before and after...