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Skip to Search Results- 1Baluch, Aliyah
- 1Bergeron, Amber
- 1Brachmann, Cole Garrett
- 1Conway, Jennifer
- 1Jin, Chaochao
- 1Kong, Jude D
- 3Department of Medicine
- 2Department of Mathematical and Statistical Sciences
- 2Faculty of Nursing
- 2School of Public Health
- 1Department of Agricultural, Food, and Nutritional Science
- 1Department of Biological Sciences
- 2Wang, Hao (Mathematical and Statistical Sciences)
- 1Anderson, Colin (Medical Microbiology and Immunology)
- 1Clandinin, M. Tom (Agricultural, Food, and Nutritional Sciences
- 1Colleen Norris (Faculty of Nursing)
- 1Deepali Kumar, MD (Transplant Infectious Diseases)
- 1Dr. Deepali Kumar (Medicine)
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Spring 2015
Background: Heart transplant is life-saving for children with end-stage congenital heart disease or acquired heart failure. Critical illness following transplantation can include acute kidney injury (AKI). There is little data on the epidemiology of, risk factors for, or impact on outcomes of...
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Characteristics of alpine plants and soils along an elevational gradient, Northern Selkirk Mountains, British Columbia
DownloadSpring 2019
Rates of climate change are accelerated at higher elevations, a pattern termed elevation-dependent warming (EDW). Consequently, the impacts of climate change on community patterning and soil development may be particularly evident in alpine environments. Alpine ecotone boundaries, such as...
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Diabetes and Influenza-Attributable Illness: The Rationale for Targeted Influenza Vaccinations in Adults with Diabetes
DownloadFall 2012
While guidelines for seasonal influenza vaccinations single out working age (< 65) adults with diabetes, vaccination rates in this group remain below national targets. Historically, there has been limited evidence to support these guidelines. This dissertation comprises four studies investigating...
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Estimating the Seroprevalence of Cytomegalovirus (CMV), Epstein-Barr Virus (EBV) and the Risk of Transfusion-Transmitted and Community-Acquired CMV Infection in Solid Organ Transplant Donors and Recipients
DownloadFall 2019
Cytomegalovirus (CMV) and Epstein-Barr virus (EBV) are ubiquitous herpesviruses that establish lifelong, often asymptomatic, infections in healthy people, but are responsible for significant morbidity and mortality in certain hosts. CMV is the most common congenital infection worldwide, causing...
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Exploring the Association between Parental Concern about Vaccine Safety and Incomplete Childhood Immunization: A Multivariate Model
DownloadSpring 2013
High levels of immunization coverage are required to maintain control of infectious diseases that previously caused significant illness and death in Canada. However, childhood immunizations have been so successful that many Canadians have never seen the impact of these diseases, with some parents...
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Spring 2013
Immunogenicity of intramuscular influenza vaccine is suboptimal in organ transplant recipients although intradermal vaccine may be superior by targeting dermal dendritic cells to stimulate a response. 229 patients were randomized to IM or high-dose ID vaccine during the 2010-11 season. Pre- and...
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Investigation of fatty acid and cholesterol synthesis using stable isotopes in type 1 diabetes, liver failure, islet and liver transplant, and effect of dietary intervention
DownloadSpring 2011
Elevated plasma lipids are risk factors for cardiovascular disease (CVD). In certain conditions plasma lipids are normal yet individuals experience increased morbidity. Type 1 diabetes (T1D) is associated with elevated CVD despite normal lipids, while in liver failure low plasma lipids may...
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Spring 2010
These two studies investigate the immune responses of lung and kidney transplant recipients to the influenza vaccine. The study involving kidney transplant recipients developed a novel flow cytometry assay to measure cell-mediated immunity in response to influenza vaccination. The activation of...
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Mathematical Models and Inverse Algorithms for Childhood Infectious Diseases with Vaccination - Case Studies in Measles
DownloadFall 2014
Children are at a high risk of infection since they have not yet developed mature immunity. Childhood infectious diseases, such as measles, chicken pox and mumps, remain epidemic and endemic around the world. Yet, their dynamics are still not fully understood. SIR-type models have been proposed...
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Fall 2017
In recent years, narratives about various embellished and imaginary risks of vaccination have come under criticism because of their implications for the widespread acceptance of vaccines. Criticisms of these narratives often accompany assumptions that all mainstream health professionals accept,...