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Skip to Search Results- 8Graduate and Postdoctoral Studies (GPS), Faculty of
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Intracellular regulation of matrix metalloproteinase-2 activity: the roles of caveolin-1 and troponin I phosphorylation
DownloadFall 2010
Matrix metalloproteinase‐2 (MMP‐2) was recently revealed to have targets and actions within the cardiac myocyte. In ischemia/reperfusion (I/R) injury, MMP‐2 is activated and degrades troponin I (TnI) and α‐actinin. The regulation of intracellular MMP‐2 activity is relatively unknown and is thus...
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Legal Agreements and the Governance of Research Commons: Lessons from Materials Sharing in Mouse Genomics
Download2014-10-24
Omics research infrastructure such as databases and bio-repositories requires effective governance to support pre-competitive research. Governance includes the use of legal agreements, such as Material Transfer Agreements (MTAs). We analyze the use of such agreements in the mouse research...
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PolySearch: A web-based text mining system for extracting relationships between human diseases, genes, mutations, drugs and metabolites
Download2008
Stothard, P., Damaraju, S., Wishart, D.S., Young, N., Cheng, D., Knox, C.
A particular challenge in biomedical text mining is to find ways of handling ‘comprehensive’ or ‘associative’ queries such as ‘Find all genes associated with breast cancer’. Given that many queries in genomics, proteomics or metabolomics involve these kind of comprehensive searches we believe...
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PolySearch: A web-based text mining system for extracting relationships between human diseases, genes, mutations, drugs and metabolites
Download2008
Cheng, Dean, Stothard, Paul, Damaraju, Sambasivarao, Wishart, David S., Knox, Craig, Young, Nelson
A particular challenge in biomedical text mining is to find ways of handling ‘comprehensive’ or ‘associative’ queries such as ‘Find all genes associated with breast cancer’. Given that many queries in genomics, proteomics or metabolomics involve these kind of comprehensive searches we believe...
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Spring 2010
A reliable estimate of the amount of oil or gas in a reservoir is required for development decisions. Uncertainty in reserve estimates affects resource/reserve classification, investment decisions, and development decisions. There is a need to make the best decisions with an appropriate level...
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2005
Xia, Q., Chen, J., Dai, M., Ye, C., Wang, J., Li, S., Li, R., Zhou, Z., Ruan, J., Hu, Y., Yu, G., Yang, H., He, X., Yu, Jun, Xiang, Z., Yuan, H., Lu, C., Feng, T.
The Silkworm Knowledgebase (SilkDB) is a web-based repository for the curation, integration and study of silkworm genetic and genomic data. With the recent accomplishment of a ~6X draft genome sequence of the domestic silkworm (Bombyx mori ), SilkDB provides an integrated representation of the...
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Spring 2018
Teaching portfolios have been used by faculty in postsecondary institutions for summative and formative evaluations since the early 1980s (Knapper, 1995). Despite their proliferation, there remains much to be learned about the use of teaching portfolios and whether they are perceived as being...
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2002
Clark, A.M., MacIntyre, P.D., Sharp, C.
Access to health care should be determined by clinical need and not by age. Older people form an increasing proportion of the general population and of those with coronary heart disease, but compared with younger people they are less likely to be invited for cardiac rehabilitation programmes and...