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Skip to Search Results- 5Gänzle, Michael G.
- 5Willing, Benjamin P.
- 4Finlay, B. Brett
- 2Antunes, L. Caetano M.
- 2Cristescu, Bogdan
- 2Croxen, Matthew A.
- 49Graduate and Postdoctoral Studies (GPS), Faculty of
- 49Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 20Agricultural, Food and Nutritional Science, Department of
- 20Agricultural, Food and Nutritional Science, Department of/Journal Articles (Agricultural, Food and Nutritional Science)
- 3Biological Sciences, Department of
- 3Biological Sciences, Department of/Journal Articles (Biological Sciences)
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Influence of sire breed on the interplay among rumen microbial populations inhabiting the rumen liquid of the progeny in beef cattle
Download2013
Guan, L. L., Wang, Z., Zhou, M., Goonewardene, L. A., Moore, S. S., Hernandez-Sanabria, E.
This study aimed to evaluate whether the host genetic background impact the ruminal microbial communities of the progeny of sires from three different breeds under different diets. Eighty five bacterial and twenty eight methanogen phylotypes from 49 individuals of diverging sire breed (Angus,...
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Initial gut microbial composition as a key factor driving host response to antibiotic treatment, as exemplified by the presence or absence of commensal Escherichia coli
Download2017-08-01
Ju, Tingting, Shoblak, Yasmeen, Gao, Yanhua, Yang, Kaiyuan, Fouhse, Janelle, Finlay, B. Brett, So, Yee Wing, Stothard, Paul, Willing, Ben P.
Antibiotics are important for treating bacterial infection; however, efficacies and side effects of antibiotics vary in medicine and experimental models. A few studies have correlated microbiota composition variations with health outcomes in response to antibiotics; however, no study has...
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Investigating early life microbial and host transcriptomic dynamics in the bovine gastrointestinal tract
DownloadSpring 2019
There is increasing concern surrounding the ability of livestock industries to meet the needs of the rising global population. The gastrointestinal microbiota of ruminants plays a critical role in feed degradation, host energy supply, but is also a substantial source of anthropogenic greenhouse...
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Investigation of fatty acid and cholesterol synthesis using stable isotopes in type 1 diabetes, liver failure, islet and liver transplant, and effect of dietary intervention
DownloadSpring 2011
Elevated plasma lipids are risk factors for cardiovascular disease (CVD). In certain conditions plasma lipids are normal yet individuals experience increased morbidity. Type 1 diabetes (T1D) is associated with elevated CVD despite normal lipids, while in liver failure low plasma lipids may...
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2012
Ketabi, Ali, Baracos, Vickie E., Field, Catherine J., Lin, Xiaoxi, Xue, Hongyu, Bibova, Ilona, Gänzle, Michael G., Dieleman, Levinus A., Sawyer, Michael B.
Intestinal microbiota mediate toxicity of irinotecan (CPT-11) cancer therapies and cause systemic infection after CPT-11-induced loss of barrier function. The intestinal microbiota and their functions are thus potential targets for treatment to mitigate CPT-11 toxicity. However, microbiota...
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Lactobacillus reuteri maintains a functional mucosal barrier during DSS treatment despite mucus layer dysfunction
Download2012
Rang, Sara, Roos, Stefan, Phillipson, Mia, Holm, Lena, Dicksved, Johan, Willing, Ben P., Petersson, Joel, Schreiber, Olof
Treatment with the probiotic bacterium Lactobacillus reuteri has been shown to prevent dextran sodium sulfate (DSS)-induced colitis in rats. This is partly due to reduced P-selectin-dependent leukocyte- and platelet-endothelial cell interactions, however, the mechanism behind this protective...
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Letter to the Editor: Comment on 'Diet quality index as a predictor of treatment efficacy in overweight and obese adolescents: The EVASYON study'
Download2020-04-01
Orsso, Camila E., Ripka, Wagner L., Prado, Carla M.
Originally published in Clinical Nutrition: https://doi.org/10.1016/j.clnu.2020.02.010
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Lipid Modified Polymers for Transfection of Human CRL Fibroblasts, and for siRNA Mediated MDR Reversal in Melanoma Cancer Therapy
DownloadFall 2010
Gene delivery for therapeutic purposes is quickly emerging as the best potential treatment option for inherited genetic diseases and cancer. Viral gene carriers have been the choice for this purpose due to their high efficiency, but harmful immunogenic and oncogenic host reactions have limited...
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Fall 2021
Spinal cord injury (SCI) not only leads to motor and sensory dysfunction, but just as debilitating are secondary consequences of SCI such as bowel disorders, neuroinflammation, immune suppression, pain and psychiatric disorders. In this thesis, I explore multiple aspects of recovery after SCI in...