Search
Skip to Search Results- 48Graduate and Postdoctoral Studies (GPS), Faculty of
- 48Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 8Biological Sciences, Department of
- 5Biological Sciences, Department of/Journal Articles (Biological Sciences)
- 3Biological Sciences, Department of/Other Publications (Biological Sciences)
- 2Roy Berg Kinsella Research Ranch
-
Genome-wide analysis of zygotic linkage disequilibrium and its components in crossbred cattle
Download2012
Jiang, Q., Wang, Z., Yang, R. C., Moore, S. S.
Background Linkage disequilibrium (LD) between genes at linked or independent loci can occur at gametic and zygotic levels known asgametic LD and zygotic LD, respectively. Gametic LD is well known for its roles in fine-scale mapping of quantitative trait loci, genomic selection and evolutionary...
-
Fall 2019
The development of efficacious anticancer therapies has significantly improved the prognosis of childhood cancer patients at the price of predisposing survivors to extensive chronic health problems. Although not fatal, reducing treatment-related hearing loss (ototoxicity) among childhood cancer...
-
Genomic Prediction of Piglet Responses to Infection with One or Two Porcine Reproductive and Respiratory Syndrome Virus Isolates
Download2018-01-01
Waide, Emily H., Tuggle, Christopher K., Serao, Nick V. I., Schroyen, Martine, Hess, Andrew, Rowland, Raymond R. R., Lunney, Joan K., Plastow, Graham, Dekkers, Jack C. M.
Genomic prediction of the pig’s response to the porcine reproductive and respiratory syndrome (PRRS) virus (PRRSV) would be a useful tool in the swine industry. This study investigated the accuracy of genomic prediction based on porcine SNP60 Beadchip data using training and validation datasets...
-
Homology in comparative, molecular, and evolutionary developmental biology: The radiation of a concept
Download2003
The present paper analyzes the use and understanding of the homology concept across different biological disciplines. It is argued that in its history, the homology concept underwent a sort of adaptive radiation. Once it migrated from comparative anatomy into new biological fields, the homology...
-
Identification of genes and gene expression associated with dispersal capacity in the mountain pine beetle, Dendroctonus ponderosae Hopkins (Coleoptera: Curculionidae)
Download2021-07-01
Shegelski, Victor A., Evenden, Maya L., Huber, Dezene P. W., Sperling, Felix A. H.
Dispersal flights by the mountain pine beetle have allowed range expansion and major damage to pine stands in western Canada. We asked what the genetic and transcriptional basis of mountain pine beetle dispersal capacity is. Using flight mills, RNA-seq and a targeted association study, we...
-
Spring 2018
Choroideremia is an X-linked monogenic inherited retinal disease. It affects males starting in their teenage years with night blindness followed by progressive vision loss starting in the peripherals and ending with total vision loss late in life. It is estimated that 1 in 50,000 individuals...
-
Fall 2017
NPAS3 encodes a transcription factor of the bHLH-PAS family, which has been robustly associated with neurodevelopmental and psychiatric disorders with intellectual disability as a common feature. NPAS3 was initially discovered as a schizophrenia-associated gene in a family with a translocation...
-
Individual Life Histories in Long-Term Culture Change: Holocene Hunter-Gatherers in Northern Eurasia
2017-10-31
SSHRC PG awarded 2018: Although 99% of human history has been lived as foragers, little is known about the contributions and experiences of individuals in hunter-gatherer groups and their role in long-term patterns of culture diversity, change, stability and resilience. We will examine these...
-
Influence of lipids (arachidonic acid and cholesterol) on calcium signalling in rodent pancreatic beta cells
DownloadFall 2010
Ca2+ is an important mediator of stimulus-secretion coupling in beta cells of the pancreatic islets, which secrete insulin in response to elevation in plasma glucose concentration. I studied the actions of two lipids, arachidonic acid (AA) and cholesterol, on enzymatically-dissociated single...
-
Innate Immunity and the Retinal Pigment Epithelium in Gene Therapy for Inherited Retinal Disorders
DownloadFall 2021
Background: The photoreceptors are post-mitotic (no longer dividing), so the eye has evolved several unique immunological mechanisms to protect the photoreceptors and prevent vision loss. Inherited retinal disorders occur when mutations disrupt normal retinal function and photoreceptors die....